Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the nuclear factor κB pathway

Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the nuclear factor κB pathway

Item
http://www.wikidata.org/entity/Q37006070
A novel role for matrix metalloproteinase-8 in sepsis.A liver-X-receptor ligand, T0901317, attenuates IgE production and airway remodeling in chronic asthma model of mice.Age-dependent therapeutic effects of liver X receptor-α activation in murine polymicrobial sepsis.Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis.Treatment with TO901317, a synthetic liver X receptor agonist, reduces brain damage and attenuates neuroinflammation in experimental intracerebral hemorrhage.Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling: A POTENTIAL ROLE FOR LIPID-PROTEIN ADDUCTS.Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense.Activation of LXRα improves cardiac remodeling induced by pulmonary artery hypertension in rats.Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hy-droxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetra-deca-hydro-1H-cyclo-penta[a]phenanthren-17-yl]-N-meth-oxy-N-methyl-pro-pan-amide (Fernholz Weinreb amide).Ethyl pyruvate significantly inhibits tumour necrosis factor-α, interleukin-1β and high mobility group box 1 releasing and attenuates sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury.
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Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the nuclear factor κB pathway

Item
http://www.wikidata.org/entity/Q37006070
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Liver X receptor α activation ...... the nuclear factor κB pathway
@en
Liver X receptor α activation ...... the nuclear factor κB pathway.
@nl
type
label
Liver X receptor α activation ...... the nuclear factor κB pathway
@en
Liver X receptor α activation ...... the nuclear factor κB pathway.
@nl
prefLabel
Liver X receptor α activation ...... the nuclear factor κB pathway
@en
Liver X receptor α activation ...... the nuclear factor κB pathway.
@nl
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Liver X receptor α activation ...... the nuclear factor κB pathway
@en
P2093
P2860
P304
P31
P356
10.1097/SHK.0B013E3181F7D742
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P478
P577
P698
P921
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