Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics.
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Applications of gene arrays in environmental toxicology: fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene.Hepatitis, rash and eosinophilia following trichloroethylene exposure: a case report and speculation on mechanistic similarity to halothane induced hepatitis.Metabolism of trichloroethyleneHuman variability and susceptibility to trichloroethylenePulmonary toxicity and carcinogenicity of trichloroethylene: species differences and modes of actionPhysiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.Evaluating noncancer effects of trichloroethylene: dosimetry, mode of action, and risk assessment.Quantitative structure-activity relationships for the developmental toxicity of haloacetic acids in mammalian whole embryo culture.Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicityInteractive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: effects on apoptosis, necrosis, and glutathione status.Trichloroethylene metabolism in the rat ovary reduces oocyte fertilizabilityOvarian gene expression is stable after exposure to trichloroethylene.Effects of Kombucha on oxidative stress induced nephrotoxicity in rats.Toxicity, biomarkers, genotoxicity, and carcinogenicity of trichloroethylene and its metabolites: a review.Sex-related differences in renal toxicodynamics in rodents.Trichloroethylene--a review of the literature from a health effects perspective.Covalent binding of xenobiotics to specific proteins in the liver.Ameliorative effect of vitamin E on trichloroethylene-induced nephrotoxicity in rats.Time-dependent autoimmune response of dichloroacetyl chloride in female MRL +/+ mice.Trichloroethylene and cancer.Lack of formic acid production in rat hepatocytes and human renal proximal tubule cells exposed to chloral hydrate or trichloroacetic acid.Trichloroethylene, trichloroacetic acid, and dichloroacetic acid: do they affect fetal rat heart development?Ability of trichloroethylene metabolite to promote immune pathology is strain-specific.Covalent binding and inhibition of cytochrome P4502E1 by trichloroethylene.Trichloroethylene metabolism in vitro: an EPR/SPIN trapping study.
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P2860
Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Consideration of the target or ...... toxicity and pharmacokinetics.
@en
Consideration of the target or ...... toxicity and pharmacokinetics.
@nl
type
label
Consideration of the target or ...... toxicity and pharmacokinetics.
@en
Consideration of the target or ...... toxicity and pharmacokinetics.
@nl
prefLabel
Consideration of the target or ...... toxicity and pharmacokinetics.
@en
Consideration of the target or ...... toxicity and pharmacokinetics.
@nl
P2860
P1476
Consideration of the target or ...... toxicity and pharmacokinetics.
@en
P2093
Beliles RP
Davidson IW
P2860
P304
P356
10.3109/03602539109029772
P407
P577
1991-01-01T00:00:00Z