Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts
about
Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathyPost-translational control of cardiac hemodynamics through myosin binding protein CCardiac MyBP-C regulates the rate and force of contraction in mammalian myocardiumPhosphorylation of tropomodulin1 contributes to the regulation of actin filament architecture in cardiac muscle.Surviving the infarct: A profile of cardiac myosin binding protein-C pathogenicity, diagnostic utility, and proteomics in the ischemic myocardium.Top-down mass spectrometry of cardiac myofilament proteins in health and disease.Sizing up models of heart failure: Proteomics from flies to humans.Cardiac troponin I Pro82Ser variant induces diastolic dysfunction, blunts β-adrenergic response, and impairs myofilament cooperativityEnhanced cardiac function in Gravin mutant mice involves alterations in the β-adrenergic receptor signaling cascadeLKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification.Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic functionSite-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics.Global comparison of phosphoproteins in human and rodent hearts: implications for translational studies of myosin light chain and troponin phosphorylations.Molecular modulation of actomyosin function by cardiac myosin-binding protein C.CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure.Cardiac myosin binding protein-C Ser302 phosphorylation regulates cardiac β-adrenergic reserveCardiac myosin-binding protein C: hypertrophic cardiomyopathy mutations and structure-function relationships.Cardiac myosin-binding protein-C is a critical mediator of diastolic function.Myofilament dysfunction as an emerging mechanism of volume overload heart failure.Pathomechanisms in heart failure: the contractile connection.Identification of cardiac myofilament protein isoforms using multiple mass spectrometry based approaches.Proteomics of pediatric heart failure: from traditional biomarkers to new discovery strategies.Contribution of Post-translational Phosphorylation to Sarcomere-Linked Cardiomyopathy Phenotypes.Roles and regulation of protein phosphatase 2A (PP2A) in the heart.Proteomics Research in Cardiovascular Medicine and Biomarker Discovery.Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart.Phosphoregulation of Cardiac Inotropy via Myosin Binding Protein-C During Increased Pacing Frequency or β1-Adrenergic Stimulation.Posttranslational modifications of calcium/calmodulin-dependent protein kinase IIδ and its downstream signaling in human failing hearts.Functional dissection of myosin binding protein C phosphorylation.Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry.Cyclic Nucleotide-Directed Protein Kinases in Cardiovascular Inflammation and Growth.Functional communication between PKC-targeted cardiac troponin I phosphorylation sites.Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy.
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Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Characterization of the cardia ...... althy and failing human hearts
@en
Characterization of the cardia ...... lthy and failing human hearts.
@nl
type
label
Characterization of the cardia ...... althy and failing human hearts
@en
Characterization of the cardia ...... lthy and failing human hearts.
@nl
prefLabel
Characterization of the cardia ...... althy and failing human hearts
@en
Characterization of the cardia ...... lthy and failing human hearts.
@nl
P2093
P2860
P1476
Characterization of the cardia ...... althy and failing human hearts
@en
P2093
Anne M Murphy
Jennifer E Van Eyk
Ronald J Holewinski
Viola Kooij
P2860
P304
P356
10.1016/J.YJMCC.2013.04.012
P577
2013-04-22T00:00:00Z