The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.
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The anti-aging and tumor suppressor protein Klotho enhances differentiation of a human oligodendrocytic hybrid cell lineThe progeroid gene BubR1 regulates axon myelination and motor function.Klotho in the cerebrospinal fluid of adults with and without Alzheimer's diseaseThe neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Life extension factor klotho enhances cognition.Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4.Variation in longevity gene KLOTHO is associated with greater cortical volumes.Klotho Regulates 14-3-3ζ Monomerization and Binding to the ASK1 Signaling Complex in Response to Oxidative Stress.Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease ProgressionRXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers.1,25(OH)2D3 dependent overt hyperactivity phenotype in klotho-hypomorphic mice.Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats.Soluble Serum αKlotho Is a Potential Predictive Marker of Disease Progression in Clear Cell Renal Cell CarcinomaExpression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood.A Novel Approach for Amplification and Purification of Mouse Oligodendrocyte Progenitor Cells.Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.Erythropoietin signaling promotes oligodendrocyte development following prenatal systemic hypoxic-ischemic brain injury.Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms.Identification of cleavage sites leading to the shed form of the anti-aging protein klothoVitamin D: a custodian of cell signalling stability in health and disease.Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.Klotho regulates CA1 hippocampal synaptic plasticity.The aging suppressor klotho: a potential regulator of growth hormone secretion.Klotho and fibroblast growth factor 23 in cerebrospinal fluid in children.Discovery of Klotho peptide antagonists against Wnt3 and Wnt3a target proteins using combination of protein engineering, protein-protein docking, peptide docking and molecular dynamics simulations.Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group.Soluble interleukin 23 receptor gene therapy with adeno-associated vectors for the treatment of multiple sclerosis.Secreted αKlotho isoform protects against age-dependent memory deficits.Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.Rat astrocytes are more supportive for mouse OPC self-renewal than mouse astrocytes in culture.Correlation between KLOTHO gene and mild cognitive impairment in the Uygur and Han populations of Xinjiang.The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination.Oligodendrocyte Lineage Cells in Chronic Demyelination of Multiple Sclerosis Optic Nerve.Changes in expression of klotho affect physiological processes, diseases, and cancer.Gene expression profile of brain regions reflecting aberrations in nervous system development targeting the process of neurite extension of rat offspring exposed developmentally to glycidol.The Expressions of Klotho Family Genes in Human Ocular Tissues and in Anterior Lens Capsules of Age-Related Cataract.Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys.FGF23 Actions on Target Tissues-With and Without Klotho.Anthocyanin bio-fortified colored wheat: Nutritional and functional characterization.
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The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The antiaging protein Klotho e ...... on and myelination of the CNS.
@en
The antiaging protein Klotho e ...... on and myelination of the CNS.
@nl
type
label
The antiaging protein Klotho e ...... on and myelination of the CNS.
@en
The antiaging protein Klotho e ...... on and myelination of the CNS.
@nl
prefLabel
The antiaging protein Klotho e ...... on and myelination of the CNS.
@en
The antiaging protein Klotho e ...... on and myelination of the CNS.
@nl
P2093
P2860
P1476
The antiaging protein Klotho e ...... on and myelination of the CNS.
@en
P2093
Alpaslan Dedeoglu
Carmela R Abraham
Ci-Di Chen
Douglas L Rosene
Ella Zeldich
Eustathia L Giannaris
Jacob A Sloane
Jason D Hinman
Jennifer I Luebke
P2860
P304
P356
10.1523/JNEUROSCI.2080-12.2013
P407
P577
2013-01-01T00:00:00Z