Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin.
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Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativitySystematic mapping of functional enhancer-promoter connections with CRISPR interference.The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution.A genome-wide association study yields five novel thyroid cancer risk loci.A viral strategy for targeting and manipulating interneurons across vertebrate species.UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracyAnalysis of cis-Regulatory Elements in Gene Co-expression Networks in Cancer.MotifHyades: Expectation Maximization for de novo DNA Motif Pair Discovery on Paired Sequences.Identification and characterization of ARS-like sequences as putative origin(s) of replication in human malaria parasite Plasmodium falciparum.ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains.A new computational method to predict transcriptional activity of a DNA sequence from diverse datasets of massively parallel reporter assays.Pathway and network-based strategies to translate genetic discoveries into effective therapies.The road to precision psychiatry: translating genetics into disease mechanisms.From profiles to function in epigenomics.Chromatin SUMOylation in heat stress: To protect, pause and organise?: SUMO stress response on chromatin.The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations.Computational challenges in modeling gene regulatory events.Advances in Genomic Profiling and Analysis of 3D Chromatin Structure and Interaction.GeneHancer: genome-wide integration of enhancers and target genes in GeneCards.The free-energy cost of interaction between DNA loops.Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes.Genome Informatics 2016.Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.Exploiting sequence-based features for predicting enhancer-promoter interactions.Genome-wide characterization of mammalian promoters with distal enhancer functions.The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivation.De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture.Integrating regulatory features data for prediction of functional disease-associated SNPs.Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development.Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers.Characteristic arrangement of nucleosomes is predictive of chromatin interactions at kilobase resolution.Statistical and integrative system-level analysis of DNA methylation data.Reconstruction of enhancer-target networks in 935 samples of human primary cells, tissues and cell lines.Gene co-opening network deciphers gene functional relationships.The interplay of epigenetic marks during stem cell differentiation and development.Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions.Characteristics of functional enrichment and gene expression level of human putative transcriptional target genes.Reconstructing spatial organizations of chromosomes through manifold learning.
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Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@en
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@nl
type
label
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@en
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@nl
prefLabel
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@en
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@nl
P2093
P2860
P356
P1433
P1476
Enhancer-promoter interactions ...... gnatures on looping chromatin.
@en
P2093
Katherine S Pollard
Rebecca M Truty
Sean Whalen
P2860
P2888
P304
P356
10.1038/NG.3539
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P577
2016-04-04T00:00:00Z