Recombinant therapeutic proteins: production platforms and challenges.
about
Risk of anaphylaxis with repeated courses of rasburicase: a Research on Adverse Drug Events and Reports (RADAR) projectLarge-scale production of pharmaceutical proteins in plant cell culture-the Protalix experienceImiglucerase and its use for the treatment of Gaucher's diseaseThe role of predictive modelling in rationally re-engineering biological systemsGlucosylglycerol and glucosylglycerate as enzyme stabilizers.Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteinsThe role of small molecules in musculoskeletal regeneration.FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein.Exploring the transcriptome space of a recombinant BHK cell line through next generation sequencing.Protein freeze concentration and micro-segregation analysed in a temperature-controlled freeze container.Mobilization of PBSC for allogeneic transplantation by the use of the G-CSF biosimilar XM02 in healthy donors.Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells.Genetic code redundancy and its influence on the encoded polypeptidesGlycosylation: impact, control and improvement during therapeutic protein production.Innovative approach for improved rFVIII concentrate.Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites.Mobilization of autologous and allogeneic peripheral blood stem cells for transplantation in haematological malignancies using biosimilar G-CSF.Effect of surfactant pluronic F-68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN-γ in mild operating conditions.Constitutive secretion in Tetrahymena thermophila.Dramatic increase in expression of a transgene by insertion of promoters downstream of the cargo gene.Design of serum-free medium for suspension culture of CHO cells on the basis of general commercial media.Elimination of β-mannose glycan structures in Pichia pastoris.Generation of fatty acids from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/cardiolipin liposomes that stabilize recombinant human serum albumin.Efficient and stable transformation of Dunaliella pseudosalina by 3 strains of Agrobacterium tumefaciens.Biosafety evaluation of recombinant protein production in goat mammary gland using adenoviral vectors: preliminary study.Growth and production of microencapsulated recombinant CHO in a stirred tank bioreactor.Modular pore-forming immunotoxins with caged cytotoxicity tailored by directed evolution
P2860
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P2860
Recombinant therapeutic proteins: production platforms and challenges.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Recombinant therapeutic proteins: production platforms and challenges.
@en
Recombinant therapeutic proteins: production platforms and challenges.
@nl
type
label
Recombinant therapeutic proteins: production platforms and challenges.
@en
Recombinant therapeutic proteins: production platforms and challenges.
@nl
prefLabel
Recombinant therapeutic proteins: production platforms and challenges.
@en
Recombinant therapeutic proteins: production platforms and challenges.
@nl
P356
P1476
Recombinant therapeutic proteins: production platforms and challenges
@en
P2093
Theo Dingermann
P356
10.1002/BIOT.200700214
P577
2008-01-01T00:00:00Z