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Isocyanide-Based Multicomponent Reactions for the Synthesis of HeterocyclesFocusing on shared subpockets - new developments in fragment-based drug discoveryEfficient isocyanide-less isocyanide-based multicomponent reactionsTransient Protein States in Designing Inhibitors of the MDM2-p53 InteractionA new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ringHighly stereoselective synthesis of natural-product-like hybrids by an organocatalytic/multicomponent reaction sequence.Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids.An Efficient Passerini Tetrazole Reaction (PT-3CR).Construction of functionalized tricyclic dihydropyrazino-quinazolinedione chemotypes via an Ugi/N-acyliminium ion cyclization cascade.A practical and efficient approach to imidazo[1,2-a]pyridine-fused isoquinolines through the post-GBB transformation strategy.Synthesis of diverse nitrogen-enriched heterocyclic scaffolds using a suite of tunable one-pot multicomponent reactions.Exploiting the Divalent Nature of Isonitriles: a novel Pictet-Spengler Amidination process.Modern Multicomponent Reactions for better Drug Syntheses**Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversificationREGIOSELECTIVE MULTICOMPONENT DOMINO REACTIONS PROVIDING RAPID AND EFFICIENT ROUTES TO FUSED ACRIDINESFour-component bicyclization approaches to skeletally diverse pyrazolo[3,4-b]pyridine derivatives.Novel potent imidazo[1,2-a]pyridine-N-Glycinyl-hydrazone inhibitors of TNF-α production: in vitro and in vivo studiesCarbohydrates as a reagent in multicomponent reactions: one-pot access to a new library of hydrophilic substituted pyrimidine-fused heterocycles.Gold-catalyzed three-component spirocyclization: a one-pot approach to functionalized pyrazolidines.High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries.Application of Silica-Supported Alkylating Reagents in a One-Pot, Sequential Protocol to Diverse Benzoxathiazepine 1,1-Dioxides.N-N bond formation in Ugi processes: from nitric acid to libraries of nitramines.A green synthetic approach toward the synthesis of structurally diverse spirooxindole derivative libraries under catalyst-free conditions.Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)-The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules.Unexpected isocyanide-based three-component bicyclization for the stereoselective synthesis of densely functionalized pyrano[3,4-c]pyrroles.MCR synthesis of a tetracyclic tetrazole scaffold.A Van Leusen deprotection-cyclization strategy as a fast entry into two imidazoquinoxaline families.BOROX catalysis: self-assembled amino-BOROX and imino-BOROX chiral Brønsted acids in a five component catalyst assembly/catalytic asymmetric aziridination.Pyridine group assisted addition of diazo-compounds to imines in the 3-CC reaction of 2-aminopyridines, aldehydes, and diazo-compounds.4-Trifluoromethyl-p-quinols as dielectrophiles: three-component, double nucleophilic addition/aromatization reactions.Aldol reactions in multicomponent reaction based domino pathways: a multipurpose enabling tool in heterocyclic chemistryToward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction.MCRs reshaped into a switchable microwave-assisted protocol toward 5-aminoimidazoles and dihydrotriazines.Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping.A Rh(II)-catalyzed multicomponent reaction by trapping an α-amino enol intermediate in a traditional two-component reaction pathway.Recent developments of ketene dithioacetal chemistry.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Recent advances in the synthesis of pyrroles by multicomponent reactions.Multicomponent reactions in nucleoside chemistry.
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Q26772038-A2689215-020B-46AC-A435-A70A8F05F5DBQ26795719-0057C7B4-96D0-40D0-A616-52558BD13A06Q27300835-9C6E5700-A96D-4068-85F4-79270101D04BQ27680560-3D884ED7-75B3-4D2A-B9DF-2F8BC3AAFA53Q28817207-3BED5AD9-A465-4CFE-A584-548249A44DBFQ30316563-7C7EEB5B-E031-4337-BAAC-3482F8BC37AEQ30317250-1B357CE1-EDD0-4450-920E-97E67B4E3000Q30355992-32B9D25D-506F-4145-B9D6-A8ED9E8B0EE8Q31136306-12736D0F-5678-434C-B8EE-DB41B8DC8D95Q33692158-9F900550-E486-45A5-9DDA-1B8ABE9064FCQ33761604-2BA2E18C-2B72-4414-ACD3-D69AF867F091Q33773093-BEB3A8A6-227B-44AF-935B-ABBA92A576B5Q34060368-DBB1CB41-E758-4548-9B76-CD055CEFD18EQ34207033-D4EFDB04-A6B4-4080-87A9-86FD39D5E148Q34429069-EE0216A9-9300-4667-92DF-E452E8B502D5Q34563970-2C4F034A-EE19-4116-BE3E-5796DB33B906Q35121833-80403B05-879E-438C-AE91-E2FD4429AB3CQ35333827-3F1A3941-B9AC-4F3D-895C-25D2169BEDB2Q35874808-73DAE798-5CC1-4EDE-A75A-75A9CD7B4047Q35952116-09FBDC4C-B232-433B-A625-F38B51ED1F65Q36051912-956AA58B-7C7C-4AE6-8779-7E8FB36BD6EDQ36263479-2F9C2FBF-C133-4430-AEBF-C4BA417FAF67Q36278024-0CB34724-1317-4BD9-B859-0FB7637560C0Q36293059-8BBF1C25-4134-47D6-94F4-EBE09478CAADQ36436882-2DDE6A18-D1AA-44E8-98A0-5E7A2FF9CC8FQ36522303-2308CB51-A436-4A3B-B447-9DBE4252E3DCQ36680142-91E0CAB0-F2FC-47C4-94A7-E65CA95F6821Q36708875-624472D4-E0B3-46B6-9015-92B90093CEE7Q36784453-16632BFF-56A7-4EA0-ADD4-B74FEF1EF566Q36953783-4AA69A84-1DCE-4E22-92A5-D0E3ED4FB4A3Q37056185-28AC83D7-FC58-4367-BDA7-7022A524826BQ37095319-DD86B1BB-DC3C-4755-96CD-CE5BE01C7858Q37164635-784226C3-22FD-4FEB-9269-812C0117AE5CQ37585590-BFE69604-9E4E-4DEF-AEAA-8204C4201983Q37671337-F098463E-C0B5-4A8E-B6D0-FCCAEA661231Q37688738-EF579C5E-AEC5-4EA3-9236-58D916E8F0AEQ38059359-3CE894E1-62CD-4E1C-AC9C-CF9646FE61C0Q38194138-AE1DB6BB-7415-400D-8CEC-517ECD393FDAQ38199956-1AD7490F-85CB-4B3A-A158-2DA51BF6EC9EQ38243795-55CE1B35-03DA-488D-8F60-963904B4B4AD
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 March 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chemistry and biology of multicomponent reactions.
@en
Chemistry and biology of multicomponent reactions.
@nl
type
label
Chemistry and biology of multicomponent reactions.
@en
Chemistry and biology of multicomponent reactions.
@nl
prefLabel
Chemistry and biology of multicomponent reactions.
@en
Chemistry and biology of multicomponent reactions.
@nl
P2860
P356
P1433
P1476
Chemistry and biology of multicomponent reactions
@en
P2093
P2860
P304
P356
10.1021/CR100233R
P50
P577
2012-03-22T00:00:00Z