Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE
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Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationDisturbances of apoptotic cell clearance in systemic lupus erythematosusLinking innate and adaptive immunity: human Vgamma9Vdelta2 T cells enhance CD40 expression and HMGB-1 secretionHigh mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptorNecroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyBreakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic CellsCirculating HMGB1 and RAGE as Clinical Biomarkers in Malignant and Autoimmune DiseasesConcepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapiesDAMPs from Cell Death to New LifeInflammatory etiopathogenesis of systemic lupus erythematosus: an updateImmune-regulatory mechanisms in systemic autoimmune and rheumatic diseasesThe role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseasesCell death and DAMPs in acute pancreatitisPAMPs and DAMPs: signal 0s that spur autophagy and immunityCell death in the pathogenesis of immune-mediated diseases: the role of HMGB1 and DAMP-PAMP complexesThe translocation of nuclear molecules during inflammation and cell deathControversial role of toll-like receptors in acute pancreatitisHow apoptotic cells aid in the removal of their own cold dead bodiesDAMPs, MAMPs, and NAMPs in plant innate immunityContribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosusHMGB1 loves companyThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityAutoimmunity in MFG-E8-deficient mice is associated with altered trafficking and enhanced cross-presentation of apoptotic cell antigensEnhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient miceDangers within: DAMP responses to damage and cell death in kidney disease.The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.Alarmins: awaiting a clinical responseCell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signalingRituximab was effective on refractory thrombotic thrombocytopenic purpura but induced a flare of hemophagocytic syndrome in a patient with systemic lupus erythematosus.Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus.Several nuclear events during apoptosis depend on caspase-3 activation but do not constitute a common pathway.Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.Pathogenesis of human systemic lupus erythematosus: recent advances.Association between high mobility group box‑1 protein expression and cell death in acute pancreatitisCirculating tumor cells promote the metastatic colonization of disseminated carcinoma cells by inducing systemic inflammationPathogenic mechanisms in systemic lupus erythematosus.Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome.Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review.Stepwise release of biologically active HMGB1 during HSV-2 infection.Novel HMGB1-inhibiting therapeutic agents for experimental sepsis.
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Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 December 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Induction of inflammatory and ...... ns for the pathogenesis of SLE
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Induction of inflammatory and ...... s for the pathogenesis of SLE.
@nl
type
label
Induction of inflammatory and ...... ns for the pathogenesis of SLE
@en
Induction of inflammatory and ...... s for the pathogenesis of SLE.
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prefLabel
Induction of inflammatory and ...... ns for the pathogenesis of SLE
@en
Induction of inflammatory and ...... s for the pathogenesis of SLE.
@nl
P2093
P2860
P50
P356
P1476
Induction of inflammatory and ...... ns for the pathogenesis of SLE
@en
P2093
Angelo A Manfredi
Barbara G Fürnrohr
Carsten Kirschning
Hermann Wagner
Joachim R Kalden
Petra Heyder
Reinhard E Voll
Silke Meister
Vilma Urbonaviciute
P2860
P304
P356
10.1084/JEM.20081165
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P50
P577
2008-12-08T00:00:00Z