Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity
about
HSF1 protects neurons through a novel trimerization- and HSP-independent mechanismIn vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs.The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease miceHistone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury.Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibitionHistone deacetylase 3 is necessary for proper brain developmentDifferential effect of HDAC3 on cytoplasmic and nuclear huntingtin aggregates.The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity.Increased Olfactory Bulb BDNF Expression Does Not Rescue Deficits in Olfactory Neurogenesis in the Huntington's Disease R6/2 Mouse.Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in RatsLoss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim.Involvement of HDAC1 and HDAC3 in the Pathology of Polyglutamine Disorders: Therapeutic Implications for Selective HDAC1/HDAC3 Inhibitors.Histone deacetylase 3 indirectly modulates tubulin acetylationInhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease.Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status.Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival.Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.MS-275, a class I histone deacetylase inhibitor, protects the p53-deficient mouse against ischemic injury.Complex neuroprotective and neurotoxic effects of histone deacetylases.Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.
P2860
Q28582569-A3D61345-0186-4C8B-9DAD-7C731F060D3CQ30591009-93F762F7-B91B-41CD-A5BB-D882B4AA826CQ33784471-EBCA95E5-90BD-4F44-BAEC-FD492F29A318Q33920945-F31B841C-E8D1-479D-AEE0-1EB0300942B6Q34309571-67E4FDB7-813D-41AA-BCA8-7FC1DCA851C2Q34383455-A9F1C6EC-AE24-48DF-AAF1-9E65F0BB64B1Q34683163-954596EA-3BAC-4929-B263-70A2A97E84C5Q35403365-BC3180D2-EB40-4AD4-9B0B-8535F09285C3Q35975087-F0F2FE7C-941C-4C29-B715-DE2026E0981BQ36515603-5A8237FD-AC4F-4352-BBE5-1B7E4CB4CA73Q36807350-EE2126E6-7B5A-4467-B24D-12195942A7CAQ37443800-1029F3AE-1610-48EE-AE93-07EDC41B7032Q37744921-25E0A4ED-5346-4D7F-B5F6-C309C7C25858Q38215303-407B3741-0D4A-45D8-AF49-20350E2D6D14Q38829277-B4924BC4-000F-4ED3-BCD5-A5C3F80A76A9Q38973133-E7ECFBF0-055D-454D-AEF7-679873B93B1EQ41161869-2C5B450F-3220-4601-A65D-C04A9797DDF1Q41861340-2467A092-9DE5-42AC-A2CE-16AE44189ADDQ42068752-1C3D84D3-CA02-4E39-BA2F-B2CCAAF69A89Q45302345-0869BBCA-0CD2-4B61-A33E-7091D6285115Q48919917-C2384B82-6279-46D1-BCBD-31184B1F20C3Q49884282-E988E1B7-5E56-4479-8365-E91EF5336A39Q50050224-9A378EB0-1117-43D0-A401-EF61A0CE53F3
P2860
Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Disassociation of histone deac ...... utant huntingtin neurotoxicity
@en
Disassociation of histone deac ...... tant huntingtin neurotoxicity.
@nl
type
label
Disassociation of histone deac ...... utant huntingtin neurotoxicity
@en
Disassociation of histone deac ...... tant huntingtin neurotoxicity.
@nl
prefLabel
Disassociation of histone deac ...... utant huntingtin neurotoxicity
@en
Disassociation of histone deac ...... tant huntingtin neurotoxicity.
@nl
P2093
P2860
P1476
Disassociation of histone deac ...... utant huntingtin neurotoxicity
@en
P2093
Farah H Bardai
Pragya Verma
Santosh R D'Mello
Varun Rawat
P2860
P304
11833-11838
P356
10.1523/JNEUROSCI.5831-12.2013
P407
P50
P577
2013-07-01T00:00:00Z