Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. - Wikidata - awgldk - TriplyDB

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

http://www.wikidata.org/entity/Q37021593

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Eag and HERG potassium channels as novel therapeutic targets in cancer Physical and functional interaction of KV10.1 with Rabaptin-5 impacts ion channel trafficking Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics Voltage-gated ion channels in cancer cell proliferation Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism Eag1 channels as potential early-stage biomarkers of hepatocellular carcinoma Ion Channels in Brain Metastasis Human EAG channels are directly modulated by PIP2 as revealed by electrophysiological and optical interference investigations Rapid internalization of the oncogenic K+ channel K(V)10.1 Functional K(v)10.1 channels localize to the inner nuclear membrane Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice Silencing of Ether à go-go 1 by shRNA inhibits osteosarcoma growth and cell cycle progression Positive correlation between the expression of hEag1 and HIF-1α in breast cancers: an observational study.The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à go-go K+ channel.Targeting potassium channels in cancer Oxidative modulation of voltage-gated potassium channels.Potassium channel ether à go-go1 is aberrantly expressed in human liposarcoma and promotes tumorigenesis Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels.In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors.Sig1R protein regulates hERG channel expression through a post-translational mechanism in leukemic cells.Cancer as a channelopathy: ion channels and pumps in tumor development and progression Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival.Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes.Short Hairpin RNA (shRNA) Ether à go-go 1 (Eag1) inhibition of human osteosarcoma angiogenesis via VEGF/PI3K/AKT signaling.Expression of eag1 channel associated with the aggressive clinicopathological features and subtype of breast cancer.p38 MAPK regulates the expression of ether à go-go potassium channel in human osteosarcoma cells.Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin.In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1.Voltage-gated potassium channels as therapeutic targets.Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System.Pharmacological modulation of voltage-gated potassium channels as a therapeutic strategy.K(+) channels as therapeutic targets in oncology.Ion channels as targets for cancer therapy Eag1 channels as potential cancer biomarkers.miRNA in the regulation of ion channel/transporter expression.The sigma-1 receptor: a regulator of cancer cell electrical plasticity?Potassium channels in cell cycle and cell proliferation.Functional properties of ion channels and transporters in tumour vascularization.

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P2860

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

http://www.wikidata.org/entity/Q37021593

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 October 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@en

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@nl

type

label

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@en

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@nl

prefLabel

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@en

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

@nl

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Journal of Biological Chemistry

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Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

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P2093

Araceli Sánchez

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Bryan R Downie

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Claudia Weber

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Constanza Contreras-Jurado

http://www.w3.org/2001/XMLSchema#string

Hendrik Knötgen

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Luis A Pardo

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Marco Gymnopoulos

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Walter Stühmer

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P2860

Ether à go-go potassium channel expression in soft tissue sarcoma patients

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion

Oncogenic potential of EAG K(+) channels

Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours.

A family of potassium channel genes related to eag in Drosophila and mammals

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Functional distinction of human EAG1 and EAG2 potassium channels

Molecular basis of the VHL hereditary cancer syndrome

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36234-36240

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scholarly article

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10.1074/JBC.M801830200

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52

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283

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2008-10-16T00:00:00Z

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18927085

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2606018

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