Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats. - Wikidata - awgldk - TriplyDB

Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.

Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.

http://www.wikidata.org/entity/Q37023109

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Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux Energy metabolism in the liver The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes.Supplementation of persimmon leaf ameliorates hyperglycemia, dyslipidemia and hepatic fat accumulation in type 2 diabetic mice.Leucine and protein metabolism in obese Zucker rats.Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp Decreased expression of hepatic glucokinase in type 2 diabetes.Defective glycogenesis contributes toward the inability to suppress hepatic glucose production in response to hyperglycemia and hyperinsulinemia in zucker diabetic fatty rats Impact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogs Gene-activation mechanisms in the regression of atherosclerosis, elimination of diabetes type 2, and prevention of dementia.Elimination of endoplasmic reticulum stress and cardiovascular, type 2 diabetic, and other metabolic diseases.Glucokinase activators for diabetes therapy: May 2010 status report Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics.Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.Regulation of hepatic energy metabolism and gluconeogenesis by BAD Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes.Molecular targeting of the GK-GKRP pathway in diabetes.Effect of adrenal medullectomy on metabolic responses to chronic intermittent hypoxia in the frequently sampled intravenous glucose tolerance test.Anti-Diabetic Effects of an Ethanol Extract of Cassia Abbreviata Stem Bark on Diabetic Rats and Possible Mechanism of Its Action: - Anti-diabetic Properties of Cassia abbreviata.Central Regulation of Glucose Production May Be Impaired in Type 2 Diabetes.Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.A high-fat, high-fructose diet accelerates nutrient absorption and impairs net hepatic glucose uptake in response to a mixed meal in partially pancreatectomized dogs.Adenovirus-mediated overexpression of Tcfe3 ameliorates hyperglycaemia in a mouse model of diabetes by upregulating glucokinase in the liver.Utilization of the Zucker Diabetic Fatty (ZDF) Rat Model for Investigating Hypoglycemia-related Toxicities.Effect of bariatric surgery combined with medical therapy versus intensive medical therapy or calorie restriction and weight loss on glycemic control in Zucker diabetic fatty rats.Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day.Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.

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Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.

http://www.wikidata.org/entity/Q37023109

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 24 October 2008

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@en

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@nl

type

label

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@en

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@nl

prefLabel

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@en

Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

@nl

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Restoration of hepatic glucoki ...... in zucker diabetic fatty rats.

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P2093

Christopher B Newgard

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Masakazu Shiota

http://www.w3.org/2001/XMLSchema#string

Noriyasu Sasaki

http://www.w3.org/2001/XMLSchema#string

Reetta L Catlin

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Richard L Printz

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Robert Chan

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Tracy P Torres

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Yuka Fujimoto

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P2860

Defect in glucokinase translocation in Zucker diabetic fatty rats

Characterization of glucokinase regulatory protein-deficient mice

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation

Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.

Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.

Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues

Gene-altered mice and metabolic flux control.

ON THE HORMONAL REGULATION OF CARBOHYDRATE METABOLISM; STUDIES WITH C14 GLUCOSE.

Sweet changes: glucose homeostasis can be altered by manipulating genes controlling hepatic glucose metabolism.

13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.

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78-86

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scholarly article

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10.2337/DB08-1119

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1

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58

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2008-10-24T00:00:00Z

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23416099

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18952838

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2606896

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