KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells
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The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergeticsEmerging functional cross-talk between the Keap1-Nrf2 system and mitochondriaMn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathwaysRadiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound.Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma.Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure.Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosis.Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.Cytotoxin-induced NADPH oxides activation: roles in regulation of cell death.6-OHDA-Induced Changes in Parkinson's Disease-Related Gene Expression are not Affected by the Overexpression of PGAM5 in In Vitro Differentiated Embryonic Mesencephalic Cells.Systematical analyses of variants in DNase I hypersensitive sites identified two novel hepatocellular carcinoma susceptibility loci among Chinese population.Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.CDK20 interacts with KEAP1 to activate NRF2 and promotes radiochemoresistance in lung cancer cells.RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells.The ratio of thioredoxin/Keap1 protein level is a predictor of distant metastasis in colorectal cancer.Redox Paradox: A novel approach to therapeutics-resistant cancer.Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model.AMP-activated protein kinase protects against necroptosis via regulation of Keap1-PGAM5 complex.
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P2860
KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
KEAP1 is a redox sensitive tar ...... ide in normal and cancer cells
@en
KEAP1 is a redox sensitive tar ...... de in normal and cancer cells.
@nl
type
label
KEAP1 is a redox sensitive tar ...... ide in normal and cancer cells
@en
KEAP1 is a redox sensitive tar ...... de in normal and cancer cells.
@nl
prefLabel
KEAP1 is a redox sensitive tar ...... ide in normal and cancer cells
@en
KEAP1 is a redox sensitive tar ...... de in normal and cancer cells.
@nl
P2093
P2860
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KEAP1 is a redox sensitive tar ...... ide in normal and cancer cells
@en
P2093
Aaron K Holley
Daret K St Clair
Kelley K Kiningham
Luksana Chaiswing
Peter A Crooks
Sumitra Miriyala
Teresa Noel
Terry D Oberley
William H St Clair
P2860
P304
P356
10.1158/0008-5472.CAN-12-4297
P407
P577
2013-05-14T00:00:00Z