Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.
about
Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational levelDirect interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant responseActivation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interactionNrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformationOridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive responseArsenic-mediated activation of the Nrf2-Keap1 antioxidant pathwayCancer in experimental animals exposed to arsenic and arsenic compoundsPlant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathwayArsenic exposure and toxicology: a historical perspectiveMolecular features in arsenic-induced lung tumorsArsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin CancerPhosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant responseOncogenomic disruptions in arsenic-induced carcinogenesis.Monomethylarsonous acid inhibited endogenous cholesterol biosynthesis in human skin fibroblasts.Pleurotus ostreatus opposes mitochondrial dysfunction and oxidative stress in acetaminophen-induced hepato-renal injury.The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells.The NRF2-KEAP1 pathway is an early responsive gene network in arsenic exposed lymphoblastoid cells.Lutein has a protective effect on hepatotoxicity induced by arsenic via Nrf2 signaling.Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β -Cell Damage.Global gene expression changes in human urothelial cells exposed to low-level monomethylarsonous acid.A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response.Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice.Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanismActivation of the Nrf2 pathway by inorganic arsenic in human hepatocytes and the role of transcriptional repressor Bach1In Vivo Effect of Arsenic Trioxide on Keap1-p62-Nrf2 Signaling Pathway in Mouse Liver: Expression of Antioxidant Responsive Element-Driven Genes Related to Glutathione Metabolism.Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stressNrf2 protects against As(III)-induced damage in mouse liver and bladder.Exposure to monomethylarsonous acid (MMA(III)) leads to altered selenoprotein synthesis in a primary human lung cell model.Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response.SILAC-Based Quantitative Proteomic Analysis Unveils Arsenite-Induced Perturbation of Multiple Pathways in Human Skin Fibroblast Cells.2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells.Tert-butylhydroquinone as a phenolic activator of Nrf2 antagonizes arsenic-induced oxidative cytotoxicity but promotes arsenic methylation and detoxication in human hepatocyte cell line.Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.USP15 negatively regulates Nrf2 through deubiquitination of Keap1.Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent mannerSodium arsenite induced reactive oxygen species generation, nuclear factor (erythroid-2 related) factor 2 activation, heme oxygenase-1 expression, and glutathione elevation in Chang human hepatocytes.Persistence of DNA damage following exposure of human bladder cells to chronic monomethylarsonous acidNrf2 promotes neuronal cell differentiationReactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling
P2860
Q24323175-E615CE42-D8D8-4B55-907F-3862AD12A55EQ24646029-7EC8E491-6CA4-4906-8717-1B5F02A3A066Q24656061-8B096982-A3EB-4942-AFB6-6EADD6B1F181Q28382823-1CADCDF9-3B6D-4E89-8DF3-FF1CE03A077AQ28383247-7686BEDF-DB1D-4F93-8EE2-A6494A2FBE1DQ28385636-C81A80FD-7DC6-48A9-BB8C-D49A196C0F15Q28386384-57B63D1A-CC7D-43E4-BF7B-39215172CEB2Q28387869-B7A784F3-740B-4462-AA59-21AC3462709CQ28391634-B18ED573-9072-4168-9CD7-C960E142FB48Q28392204-E0B99228-0502-471E-8BF7-DA92D49DBE39Q28396910-1D65618B-165C-49F1-B4F7-6CBF5531BBB9Q29248928-2D9A1153-47B3-4B15-B058-4FF2CC5FBB89Q33492309-ECFFA6F9-7C08-4BFA-9492-027B936514CAQ33649020-2770175B-60A9-4A00-BCCA-BACA38325CA4Q33683916-CEF0E88E-A46F-4F26-A202-CA22543B7A9BQ34993617-E7B135F9-1B55-4288-B0B7-7928BC5722B1Q35006065-D01870D3-E2FF-41D9-8682-DBD56DFD32D0Q35091522-9BB2F539-A61E-4565-8B8C-3DDF819D86F6Q35169978-111CB3C8-9080-4134-9EDE-A178C99C87EDQ35531066-DA19488B-967A-48D0-BF56-505BC83EB7BAQ35633033-016A87A0-9114-4FA8-828D-A57E83838BCBQ36030282-3227B184-3856-4FD4-AE2C-8EBC5462E570Q36227733-E72D3A1A-014A-4BCD-8F63-4E97E92A0DCFQ36845095-1D5BE995-2FBA-4466-83D6-E218999E0621Q36877171-80D6DAF5-B8DD-48D5-BC63-A6F5F0147E57Q36962021-E6DC6C30-CC38-42AA-AF56-C3180D959C5EQ37010338-9039BDAD-72ED-43AE-BE88-92CD354E55D8Q37337875-C47D7301-7606-4D69-8A79-69A4DBD08943Q37378846-096BC25C-2E98-4B71-BF57-DC1A37A49360Q37598098-BE3291ED-1497-40AD-983F-CEE1EFCF1E65Q38403001-813088D5-F053-4218-9912-C400E199F60EQ38832666-6F58E074-B1A6-491A-84A3-459EE99E94C7Q38980669-D27CF67D-6EF7-4B3D-8F86-898FE467AE38Q39076617-EE7467D5-28BF-4D9E-A709-D87C50F118A3Q39145102-FA2FA53F-70D3-4B95-A9A6-4F9257FDB383Q39165710-1A33AA4F-0E55-41A7-988E-F91C3BDA8DE7Q39496444-26227D92-33A5-4F53-8526-374B328DB49EQ39809704-D4A4F596-9135-40DA-B4E8-8C23E6ADF6C3Q39830008-9D5A5363-7C60-4004-B2A1-7B594C31C4F0Q39915556-99D15D8C-F885-4FFA-969C-F2B7BD2901DD
P2860
Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 August 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@en
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@nl
type
label
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@en
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@nl
prefLabel
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@en
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@nl
P2093
P2860
P1476
Nrf2 protects human bladder ur ...... omethylarsonous acid toxicity.
@en
P2093
Donna D Zhang
Jay A Gandolfi
Kylee E Eblin
Weimin Chen
Xiao-Jun Wang
P2860
P304
P356
10.1016/J.TAAP.2007.07.016
P577
2007-08-07T00:00:00Z