Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer. - Wikidata - awgldk - TriplyDB

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.

http://www.wikidata.org/entity/Q37031288

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Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming Advances in targeting signal transduction pathways Reciprocal regulation between microRNAs and epigenetic machinery in colorectal cancer.β2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cells.Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity.Histones: Controlling Tumor Signaling Circuitry Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities.Sorting out functions of sirtuins in cancer SIRT1 inactivation evokes antitumor activities in NSCLC through the tumor suppressor p27.SIRT1 expression is associated with lymphangiogenesis, lymphovascular invasion and prognosis in pN0 esophageal squamous cell carcinoma.ELL targets c-Myc for proteasomal degradation and suppresses tumour growth.Prognostic and clinical value of Sirt1 expression in gastric cancer: A systematic meta-analysis.Geroconversion: irreversible step to cellular senescence Expression of PI3Kp110α and PI3Kp110β in the colorectal conventional adenoma, serrated lesions and adenoma with canceration and their significance Carcinoma of the gastroesophageal junction in Chinese patients.Expression and clinical significance of Sirt1 in colorectal cancer.Revealing potential molecular targets bridging colitis and colorectal cancer based on multidimensional integration strategy.The emerging and diverse roles of sirtuins in cancer: a clinical perspective.Epigenetic effects of natural polyphenols: a focus on SIRT1-mediated mechanisms.Immunohistochemical Characterization of Large Intestinal Adenocarcinoma in the Rhesus Macaque (Macaca mulatta).Protein-protein interaction analysis of distinct molecular pathways in two subtypes of colorectal carcinoma Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach.KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance.SIRT1 controls cell proliferation by regulating contact inhibition.Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target.Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer.Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene.Impact of reassessment of colonic hyperplastic polyps by expert GI pathologists.Meta-analysis of SIRT1 expression as a prognostic marker for overall survival in gastrointestinal cancer.Distribution of the c-MYC gene product in colorectal neoplasia.Let-7d increases ovarian cancer cell sensitivity to a genistein analog by targeting c-Myc.[In situ analyses of molecular mechanisms of colorectal carcinogenesis].SIRT1 regulates Mxd1 during malignant melanoma progression.Evolving notions on immune response in colorectal cancer and their implications for biomarker development.O-Linked N-Acetylglucosamine (O-GlcNAc) Expression Levels Epigenetically Regulate Colon Cancer Tumorigenesis by Affecting the Cancer Stem Cell Compartment via Modulating Expression of Transcriptional Factor MYBL1.SIRT1 overexpression is an independent prognosticator for patients with esophageal squamous cell carcinoma.[c-MYC-mediated regulations in colorectal cancer].

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P2860

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.

http://www.wikidata.org/entity/Q37031288

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on October 2012

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@en

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@nl

type

label

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@en

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@nl

prefLabel

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@en

Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@nl

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Up-regulation of c-MYC and SIR ...... ed route to colorectal cancer.

@en

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Lydia Kriegl

http://www.w3.org/2001/XMLSchema#string

Michael Vieth

http://www.w3.org/2001/XMLSchema#string

Thomas Kirchner

http://www.w3.org/2001/XMLSchema#string

P2860

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability

Identification of c-MYC as a target of the APC pathway

Sirt1 deacetylates c-Myc and promotes c-Myc/Max association

SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

Wnt/beta-catenin signaling in development and disease

Genetic alterations during colorectal-tumor development

Progressive loss of SIRT1 with cell cycle withdrawal.

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1182-1193

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scholarly article

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10.18632/ONCOTARGET.628

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10

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3

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2012-10-01T00:00:00Z

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232223567

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23045412

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colorectal cancer

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3717960

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