Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer. - Wikidata - awgldk - TriplyDB

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

http://www.wikidata.org/entity/Q37032635

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Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3 Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis Galectin-1 exerts inhibitory effects during DENV-1 infection Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics NMR and MD investigations of human galectin-1/oligosaccharide complexes Galectins and gliomas.Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.Emerging role of alpha2,6-sialic acid as a negative regulator of galectin binding and function.Molecular alterations in glioblastoma: potential targets for immunotherapy.Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress.Roles of galectins in infection Galectin-1 signaling in leukocytes requires expression of complex-type N-glycans.Parasitic helminths: a pharmacopeia of anti-inflammatory molecules.MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma.Re-wiring regulatory cell networks in immunity by galectin-glycan interactions.Galectin-1 inhibitors and their potential therapeutic applications: a patent review.Galectin-1 induces vascular permeability through the neuropilin-1/vascular endothelial growth factor receptor-1 complex.Regulation of Eosinophil Recruitment and Activation by Galectins in Allergic Asthma.Biomarkers of metastatic potential in cultured adenocarcinoma clones.The clinical implication of tumoral Gal-1 expression in laryngeal squamous cell carcinomas.Computational studies of human galectin-1: role of conserved tryptophan residue in stacking interaction with carbohydrate ligands.Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation.Exploring the Structural Space of the Galectin-1-Ligand Interaction.Apoptosis and anergy of T cell induced by pancreatic stellate cells-derived galectin-1 in pancreatic cancer.Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion

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P2860

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

http://www.wikidata.org/entity/Q37032635

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@en

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@nl

type

label

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@en

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@nl

prefLabel

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@en

Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@nl

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14712598.8.1.45

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Expert Opinion on Biological Therapy

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Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.

@en

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Diego O Croci

http://www.w3.org/2001/XMLSchema#string

Gabriel A Rabinovich

http://www.w3.org/2001/XMLSchema#string

Germán A Bianco

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Mariana Salatino

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Marta A Toscano

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P2860

Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells

Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation

Intracellular functions of galectins

Galectins and cancer

Increased alpha2,6-sialylation of surface proteins on tolerogenic, immature dendritic cells and regulatory T cells

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

Immunosuppressive strategies that are mediated by tumor cells

Galectin-1 supports survival of naive T cells without promoting cell proliferation.

Proteomic profiling identifies breast tumor metastasis-associated factors in an isogenic model

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45-57

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scholarly article

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10.1517/14712598.8.1.45

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1

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8

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Juan M. Ilarregui

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2008-01-01T00:00:00Z

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5766222

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18081536

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