Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point
about
Genetic evolution of low pathogenecity H9N2 avian influenza viruses in Tunisia: acquisition of new mutations.Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.T-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge.Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parametersViral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania.Immune and viral correlates of "secondary viral control" after treatment interruption in chronically HIV-1 infected patients.Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression.Challenges in the design of a T cell vaccine in the context of HIV-1 diversity.Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.The T-cell response to HIV.Rapid disease progression in HIV-1 subtype C-infected South African women.Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.Virological and immunological factors associated with HIV-1 differential disease progression in HLA-B 58:01-positive individualsLimited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infectionFitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infectionBroad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infectionTemporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression.Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progressionHLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703Enhancement of viral escape in HIV-1 Nef by STEP vaccination.Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa.Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point.Measuring inhibition of HIV replication by ex vivo CD8⁺ T cells.ELISpot for measuring human immune responses to vaccines.Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines.Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques.Conserved HIV-1 Gag p24 Epitopes Elicit Cellular Immune Responses That Impact Disease Outcome.Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.Phenotype, Polyfunctionality, and Antiviral Activity of Stimulated CD8 T-Cells From HIV Subjects Who Initiated cART at Different Time-Points After Acute Infection
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Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human immunodeficiency virus-s ...... ourse of viremia and set point
@en
Human immunodeficiency virus-s ...... urse of viremia and set point.
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type
label
Human immunodeficiency virus-s ...... ourse of viremia and set point
@en
Human immunodeficiency virus-s ...... urse of viremia and set point.
@nl
prefLabel
Human immunodeficiency virus-s ...... ourse of viremia and set point
@en
Human immunodeficiency virus-s ...... urse of viremia and set point.
@nl
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Human immunodeficiency virus-s ...... ourse of viremia and set point
@en
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CAPRISA 002 Acute Infection Study Team
Cathal Seoighe
Catherine Riou
Debra de Assis Rosa
Mandla Mlotshwa
Nobubelo Ngandu
Tiyani Mathebula
Tumelo Mashishi
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P304
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10.1128/JVI.01678-08
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P577
2008-10-22T00:00:00Z