Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
about
Lipopolysaccharide hyperpolarizes guinea pig airway epithelium by increasing the activities of the epithelial Na+ channel and the Na+ - K+ pumpProteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-SRegulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)The Epithelial Sodium Channel and the Processes of Wound HealingCPT-cGMP Is A New Ligand of Epithelial Sodium ChannelsEpithelial Na(+) channel regulation by cytoplasmic and extracellular factorsThe epithelial sodium channel δ-subunit: new notes for an old songASIC and ENaC type sodium channels: conformational states and the structures of the ion selectivity filtersThe pannexin 1 channel activates the inflammasome in neurons and astrocytesDevelopmental changes of ENaC expression and function in the inner ear of pendrin knock-out mice as a perspective on the development of endolymphatic hydrops.The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersConstraint-based, homology model of the extracellular domain of the epithelial Na+ channel α subunit reveals a mechanism of channel activation by proteases.Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.Intersubunit conformational changes mediate epithelial sodium channel gating.Identification of epithelial Na+ channel (ENaC) intersubunit Cl- inhibitory residues suggests a trimeric alpha gamma beta channel architecture.Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleftBase of the thumb domain modulates epithelial sodium channel gating.Cpt-cAMP activates human epithelial sodium channels via relieving self-inhibitionSecond transmembrane domain modulates epithelial sodium channel gating in response to shear stressExternal Cu2+ inhibits human epithelial Na+ channels by binding at a subunit interface of extracellular domains.ENaC structure and function in the wake of a resolved structure of a family member.8-(4-chlorophenylthio)-guanosine-3',5'-cyclic monophosphate-Na stimulates human alveolar fluid clearance by releasing external Na+ self-inhibition of epithelial Na+ channelsRegulatory Effects of Ca2+ and H+ on the Rat Chorda Tympani Response to NaCl and KCl.Functional Roles of Clusters of Hydrophobic and Polar Residues in the Epithelial Na+ Channel Knuckle Domain.Cathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.Probing the structural basis of Zn2+ regulation of the epithelial Na+ channel.Identification of extracellular domain residues required for epithelial Na+ channel activation by acidic pHChanges in taste receptor cell [Ca2+]i modulate chorda tympani responses to salty and sour taste stimuli.Ubiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channelStructural mechanisms underlying the function of epithelial sodium channel/acid-sensing ion channel.Insights into the molecular determinants of proton inhibition in an acid-inactivated degenerins and mammalian epithelial Na(+) channel.Extracellular chloride regulates the epithelial sodium channel.Deletion of α-subunit exon 11 of the epithelial Na+ channel reveals a regulatory moduleHypoxia and Its Acid-Base Consequences: From Mountains to Malignancy.Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel.Activation of the Human Epithelial Sodium Channel (ENaC) by Bile Acids Involves the Degenerin Site.Versatility of NaCl transport mechanisms in the cortical collecting duct.Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel.Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors.
P2860
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P2860
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
@en
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition.
@nl
type
label
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
@en
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition.
@nl
prefLabel
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
@en
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition.
@nl
P2860
P356
P1476
Extracellular protons regulate human ENaC by modulating Na+ self-inhibition
@en
P2093
Daniel M Collier
Peter M Snyder
P2860
P304
P356
10.1074/JBC.M806954200
P407
P577
2008-11-06T00:00:00Z