Cell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus.
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RNase L restricts the mobility of engineered retrotransposons in cultured human cellsPKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5AEvaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses.Predicted structure and domain organization of rotavirus capping enzyme and innate immune antagonist VP3Mouse hepatitis virus infection upregulates genes involved in innate immune responses.Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responsesThe nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU.Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.Intracranial Injection of Dengue Virus Induces Interferon Stimulated Genes and CD8+ T Cell Infiltration by Sphingosine Kinase 1 Independent PathwaysEarly endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationGlucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB SignalingActivation of RNase L is dependent on OAS3 expression during infection with diverse human virusesActivation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced InterferonMiddle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus MutantsAntagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes.Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.Cell-type-specific effects of RNase L on viral induction of beta interferon.Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages.Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity.
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Cell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cell-type-specific activation ...... thway by a murine coronavirus.
@en
Cell-type-specific activation ...... thway by a murine coronavirus.
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type
label
Cell-type-specific activation ...... thway by a murine coronavirus.
@en
Cell-type-specific activation ...... thway by a murine coronavirus.
@nl
prefLabel
Cell-type-specific activation ...... thway by a murine coronavirus.
@en
Cell-type-specific activation ...... thway by a murine coronavirus.
@nl
P2093
P2860
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Cell-type-specific activation ...... athway by a murine coronavirus
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Judith Grinspan
Judith M Phillips
Kristine M Rose
L Dillon Birdwell
P2860
P304
P356
10.1128/JVI.00769-13
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P577
2013-05-22T00:00:00Z