Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening - Wikidata - awgldk - TriplyDB

Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening

Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening

http://www.wikidata.org/entity/Q37036912

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Physical view on migration modes Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices.Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression Cellular and physical mechanisms of branching morphogenesis.Dynamic reciprocity between cells and their microenvironment in reproduction.Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1.New insight into the role of MMP14 in metabolic balance.SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling.Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype.Of plasticity and specificity: dialectics of the micro- and macro-environment and the organ phenotype.Extracellular matrix and cytoskeletal dynamics during branching morphogenesis.The role of tumor microenvironment in collective tumor cell invasion.Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy.Oxygen diffusion and consumption in extracellular matrix gels: implications for designing three-dimensional cultures.Building branched tissue structures: from single cell guidance to coordinated construction.Functional roles of MMP14 and MMP15 in early postnatal mammary gland development.Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP-14.Dysregulated Collagen Homeostasis by Matrix Stiffening and TGF-β1 in Fibroblasts from Idiopathic Pulmonary Fibrosis Patients: Role of FAK/Akt.Epithelial contribution to the profibrotic stiff microenvironment and myofibroblast population in lung fibrosis.Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells.The nanomechanical signature of breast cancer

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Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening

http://www.wikidata.org/entity/Q37036912

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 13 October 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Collective epithelial cell inv ...... MP14-dependent local softening

@en

Collective epithelial cell inv ...... P14-dependent local softening.

@nl

type

label

Collective epithelial cell inv ...... MP14-dependent local softening

@en

Collective epithelial cell inv ...... P14-dependent local softening.

@nl

prefLabel

Collective epithelial cell inv ...... MP14-dependent local softening

@en

Collective epithelial cell inv ...... P14-dependent local softening.

@nl

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Integrative Biology

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Collective epithelial cell inv ...... MP14-dependent local softening

@en

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Cyrus M Ghajar

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Hidetoshi Mori

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Mina J Bissell

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Roland Galgoczy

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P2860

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

Cell movement is guided by the rigidity of the substrate.

Tensional homeostasis and the malignant phenotype

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

The relation between load and penetration in the axisymmetric boussinesq problem for a punch of arbitrary profile

Collective cell migration in morphogenesis, regeneration and cancer

Plasticity of cell migration: a multiscale tuning model

The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium.

Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis.

Actin filament dynamics in living glial cells imaged by atomic force microscopy.

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1153-1166

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scholarly article

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10.1039/C1IB00073J

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12

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3

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Doug Brownfield

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2011-10-13T00:00:00Z

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51714165

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21993836

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extracellular matrix

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3719864

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