Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography.
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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexesBinding and internalization of somatostatin, insulin, and glucagon by cultured rat islet cellsInhibitors of protein synthesis also inhibit lysosomal proteolysis. Studies using cystinotic fibroblasts.Hepatic glucagon metabolism. Correlation of hormone processing by isolated canine hepatocytes with glucagon metabolism in man and in the dog.Binding, internalization, and lysosomal association of 125I-human growth hormone in cultured human lymphocytes: a quantitative morphological and biochemical studySurface redistribution of 125I-insulin in cultured human lymphocytesBiochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytesEndocytosis and the recycling of plasma membraneCoated vesicles participate in the receptor-mediated endocytosis of insulinIsolation and characterization of multivesicular bodies from rat hepatocytes: an organelle distinct from secretory vesicles of the Golgi apparatusIntracellular pathway followed by the insulin receptor covalently coupled to 125I-photoreactive insulin during internalization and recycling.Selective degradation of insulin within rat liver endosomes.Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.Internalized insulin receptors are recycled to the cell surface in rat hepatocytesReceptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesiclesInsulin is ubiquitous in extrapancreatic tissues of rats and humansRegulation of insulin receptors: evidence for involvement of an endocytotic internalization pathwayInsulin receptor kinase activation releases a constraint maintaining the receptor on microvilli.Internalization pathway of C3b receptors in human neutrophils and its transmodulation by chemoattractant receptors stimulation.Receptor-linked degradation of 125I-insulin is mediated by internalization in isolated rat hepatocytes.Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study.Surface binding and internalization of platelet-derived growth factor in human fibroblasts.The insulin receptor: structure and function.Protein kinase activity of the insulin receptorProlonged effect of insulin on glucose uptake by rat skeletal muscleDifferences in degradation processes for insulin and its receptor in cultured foetal hepatocytes.Involvement of hormone processing in insulin-activated glucose transport by isolated cardiac myocytes.In vitro recovery of insulin binding after downregulation in cultured normal human monocytes.Role of hepatocyte plasma membrane in insulin degradation.Insulin activates the plasma-membrane and dense-vesicle cyclic AMP phosphodiesterase in hepatocytes by distinct routes.Receptor- and non-receptor-mediated uptake and degradation of insulin by hepatocytes.The fate of insulin in cardiac muscle. Studies on isolated muscle cells from adult rat heart.Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes.Receptor-mediated insulin degradation and insulin-stimulated glycogenesis in cultured foetal hepatocytes.Insulin binding, internalization, and receptor regulation in cultured human fibroblasts.Metabolic effects of bacitracin in isolated rat hepatocytes.Binding of concanavalin A to isolated hepatocytes and its effect on uptake and degradation of asialo-fetuin by the cells.Evidence for a direct effect of bacitracin on cell-mediated insulin degradation in isolated hepatocytes.Insulin binding to liver plasma membranes from rats rendered diabetic by alloxan. A kinetic demonstration of two classes of binding sites in equilibrium with each other.In vivo characterization of insulin uptake by dog renal cortical epithelium.
P2860
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P2860
Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Lysosomal association of inter ...... n microscopic autoradiography.
@en
Lysosomal association of inter ...... n microscopic autoradiography.
@nl
type
label
Lysosomal association of inter ...... n microscopic autoradiography.
@en
Lysosomal association of inter ...... n microscopic autoradiography.
@nl
prefLabel
Lysosomal association of inter ...... n microscopic autoradiography.
@en
Lysosomal association of inter ...... n microscopic autoradiography.
@nl
P2093
P2860
P356
P1476
Lysosomal association of inter ...... n microscopic autoradiography.
@en
P2093
P2860
P304
P356
10.1172/JCI109420
P407
P577
1979-06-01T00:00:00Z