Signal transducing membrane complexes of photoreceptor outer segments.
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G-protein betagamma-complex is crucial for efficient signal amplification in visionRetinal remodeling in human retinitis pigmentosaProtein and Signaling Networks in Vertebrate Photoreceptor CellsSpecialized Cilia in Mammalian Sensory SystemsLocalization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25Targeting of Drosophila rhodopsin requires helix 8 but not the distal C-terminusProteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degenerationEvolution of Vertebrate Phototransduction: Cascade ActivationSpeed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and modelsVariation in Rhodopsin Kinase Expression Alters the Dim Flash Response Shut Off and the Light Adaptation in Rod PhotoreceptorsOptogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOpMembrane guanylyl cyclase complexes shape the photoresponses of retinal rods and cones.Novel functions of photoreceptor guanylate cyclases revealed by targeted deletionStructural requirements of the photoreceptor phosphodiesterase gamma-subunit for inhibition of rod PDE6 holoenzyme and for its activation by transducin.Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.Membrane guanylate cyclase, a multimodal transduction machine: history, present, and future directionsStructural characterization of the rod cGMP phosphodiesterase 6.Speed, adaptation, and stability of the response to light in cone photoreceptors: the functional role of Ca-dependent modulation of ligand sensitivity in cGMP-gated ion channelsMolecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modelingCyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.N-terminal half of the cGMP phosphodiesterase gamma-subunit contributes to stabilization of the GTPase-accelerating protein complexRAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segmentsRod phosphodiesterase-6 (PDE6) catalytic subunits restore cone function in a mouse model lacking cone PDE6 catalytic subunit.Activation and quenching of the phototransduction cascade in retinal cones as inferred from electrophysiology and mathematical modelingMembrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptorsLong-term preservation of cone photoreceptors and restoration of cone function by gene therapy in the guanylate cyclase-1 knockout (GC1KO) mouse.Steric volume exclusion sets soluble protein concentrations in photoreceptor sensory cilia.Structural and functional protein network analyses predict novel signaling functions for rhodopsin.Ca(2+)-sensors and ROS-GC: interlocked sensory transduction elements: a review.Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex.Characterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6).Functional mapping of interacting regions of the photoreceptor phosphodiesterase (PDE6) γ-subunit with PDE6 catalytic dimer, transducin, and regulator of G-protein signaling9-1 (RGS9-1).Organization of cGMP sensing structures on the rod photoreceptor outer segment plasma membrane.Protein sorting, targeting and trafficking in photoreceptor cellsMonomeric rhodopsin is the minimal functional unit required for arrestin binding.Evolution of vertebrate rod and cone phototransduction genes.Lipid second messengers and related enzymes in vertebrate rod outer segments.Phototransduction motifs and variations.Clinical and molecular genetics of the phosphodiesterases (PDEs).Intravitreal Injection of Normal Saline Induces Retinal Degeneration in the C57BL/6J Mouse.
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P2860
Signal transducing membrane complexes of photoreceptor outer segments.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Signal transducing membrane complexes of photoreceptor outer segments.
@en
Signal transducing membrane complexes of photoreceptor outer segments.
@nl
type
label
Signal transducing membrane complexes of photoreceptor outer segments.
@en
Signal transducing membrane complexes of photoreceptor outer segments.
@nl
prefLabel
Signal transducing membrane complexes of photoreceptor outer segments.
@en
Signal transducing membrane complexes of photoreceptor outer segments.
@nl
P2860
P1433
P1476
Signal transducing membrane complexes of photoreceptor outer segments.
@en
P2093
Theodore G Wensel
P2860
P304
P356
10.1016/J.VISRES.2008.03.010
P577
2008-05-05T00:00:00Z