Intracellular antibody receptor TRIM21 prevents fatal viral infection. - Wikidata - awgldk - TriplyDB

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

http://www.wikidata.org/entity/Q37049349

about

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases Coordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21 Role of Fc in antibody-mediated protection from ricin toxin TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.Intracellular sensing of complement C3 activates cell autonomous immunity.Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens IgG subclasses and allotypes: from structure to effector functions.TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus.Lysine11-Linked Polyubiquitination of the AnkB F-Box Effector of Legionella pneumophila.Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells.Innate immunity to adenovirus.TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity.Intracellular antibody immunity.Protective role of mouse IgG1 in cryoglobulinaemia; insights from an animal model and relevance to human pathology.Mouse and human FcR effector functions.Monoclonal antibodies: technologies for early discovery and engineering.TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity Downregulation of TRIM21 contributes to hepatocellular carcinoma carcinogenesis and indicates poor prognosis of cancers.Ubiquitin enzymes in the regulation of immune responses.The TRIMendous Role of TRIMs in Virus-Host Interactions.Antibody-antigen kinetics constrain intracellular humoral immunity.Antibody- and TRIM21-dependent intracellular restriction of Salmonella enterica.Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.Autoantibodies against the Immunoglobulin-Binding Region of Ro52 Link its Autoantigenicity with Pathogen Neutralization.TRIM21 Promotes Innate Immune Response to RNA Viral Infection through Lys27-linked Polyubiquitination of MAVS.Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.

P2860

Q26779753-4A9F09F4-648A-406C-B25B-01192A2EC95B Q26783175-884C089C-7ECA-4C42-A483-2A0DF31271EC Q28078936-51443C07-E6EB-4CF6-B3F9-8810EF625606 Q33736516-94464C77-4375-467A-B11B-42422EBAF110 Q33899190-D7EFD652-4BA0-4AB5-B0A9-8A2414B6260F Q34231523-A452CC5F-803E-4774-83DA-D0A1D19FE7E0 Q34319249-162A3942-F2FC-46BB-BD09-5E349B6B164A Q34368678-8DAB14BE-C726-425A-9471-A3730E157F0D Q35823139-C46F1944-9899-48D8-8425-4AD136F6C814 Q36411018-850B233A-A5DF-4747-822B-E99D9CAC8C04 Q36764988-4E3CEE08-CF73-4D41-97D5-D4F882903D92 Q37579656-CB71F41F-B644-41BF-9400-A2BA93CBF7DE Q37718852-234F807D-7F9C-4CCA-997D-A1F9A89E3D33 Q38170892-A4DAB760-DA85-4CDF-B2CA-B4925406DAFB Q38203800-B5CCB1F6-9FE7-41A5-B08C-CE4C7FEC614A Q38593866-4E25A7D9-7AF9-419A-9DF9-63C73AE40C50 Q38615349-6FDD4BDE-F4DA-4CD1-9E1C-EA1CCC98885D Q38633596-618D072D-1CCF-4E3A-A7A0-A3D9A6089772 Q38787430-AB64C996-4A2E-4A26-AA97-19F5EA63236F Q38866108-B440B382-EE14-4C68-AF88-CA7E691CDFDA Q39317949-049DFC38-5711-4B1F-88A8-B824EE88F4E8 Q40075519-70034FEE-23EA-4136-916A-47FF0B662CD0 Q40437803-3A8F04EC-060B-410F-9DD8-8828076B498C Q42213058-ECB697DA-ECFF-470A-9095-EA58595FA588 Q47271003-1C2F8C7B-EF29-4D19-A53A-41CB87E4B0FA Q49789469-35B92A67-0CC9-4DC2-81FF-A8E7B509EF1E Q54216824-8943AD19-8F35-461D-B507-86F9E72E3BEC Q55044025-F8319FB1-1B75-417F-9934-6324AC54388A

P2860

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

http://www.wikidata.org/entity/Q37049349

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 09 July 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@en

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@nl

type

label

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@en

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@nl

prefLabel

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@en

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@nl

P1433

Q37049349-9E310287-04EC-4BDD-9AD1-1C98939273B8

P1476

Q37049349-01EC72E7-DF4D-41E6-84E5-3CE2F0C3CCA5

P2093

Q37049349-2AB480E9-C8FB-47DB-9901-7F1EBF33FAE8

Q37049349-464AB4D2-7080-4BE4-BAD7-64772F36F65F

Q37049349-6A266EAB-A892-47FE-BD9A-B7C063BFD2AC

Q37049349-BE5915FA-D5E3-46DE-9AF8-C13B677E5865

Q37049349-C928FF40-E3FF-49AB-A797-70CACACE8C6B

Q37049349-D6D19DC5-7C4A-445B-A48C-BA496F7BC2B4

Q37049349-FDB7D8AC-DC58-4A90-9DFC-74F7C3BDC03D

P2860

Q37049349-37908878-6EA8-416E-AADA-5B96E2BF4D27

Q37049349-4213A98B-169D-4333-B20C-6FD36EDA3402

Q37049349-5CB8497F-6C0C-4B5E-9DA3-16A4426A4BE4

Q37049349-60EBC3BA-9BC8-4D16-893E-54F10C3DCD9A

Q37049349-645E7711-B18A-4B37-8647-01FB5C67B32E

Q37049349-755EE45B-2D29-4A6D-96FC-A7E2503CE1AB

Q37049349-78A43064-041C-4F66-A224-F173F6E5FAB1

Q37049349-8E8FC0A1-80AD-44DB-84C7-E24A049B4B39

Q37049349-903F1265-8A23-44EB-B03C-6C1A7F4AFE8F

Q37049349-96EB4B83-BCA2-4CBD-912F-7BDFAE2E36AA

P304

Q37049349-F983D73F-50EA-4865-90E0-80FE0520A27F

P31

Q37049349-32DF972A-78EA-4C07-910C-6E46A921E32A

P356

Q37049349-477C0BB2-7F99-4174-9A95-C78BBCD76DDE

P407

Q37049349-0F5A259C-0D2C-4868-AD5C-AE42C1A8B077

P433

Q37049349-FBB490F1-342B-4E64-B7C4-93920B4653A5

P478

Q37049349-44D80EA1-2DEA-4A5E-8F65-C8B6135E624A

P50

Q37049349-29A8C9CC-4F33-49A9-ABC8-60B94356BFA4

P577

Q37049349-836FCCB7-5CA2-4162-B922-8F5D249FDEF8

P5875

Q37049349-491BF7D5-5E0C-4CF0-AD7E-A9A637F9BB4D

P698

Q37049349-6E0C925F-C975-446C-AE58-AD2C180B4CF8

P921

Q37049349-CC582146-2B9D-49C1-B0EF-6740231A3357

P932

Q37049349-262314FC-230C-4599-B468-5CA034CA99E4

P356

PNAS.1301918110

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Intracellular antibody receptor TRIM21 prevents fatal viral infection.

@en

P2093

Helen Cooper

http://www.w3.org/2001/XMLSchema#string

Jackie Smith

http://www.w3.org/2001/XMLSchema#string

James Cruickshanks

http://www.w3.org/2001/XMLSchema#string

Kevin O'Connell

http://www.w3.org/2001/XMLSchema#string

Leo C James

http://www.w3.org/2001/XMLSchema#string

Marina Vaysburd

http://www.w3.org/2001/XMLSchema#string

Martin Reed

http://www.w3.org/2001/XMLSchema#string

P2860

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function

TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

Mouse adenovirus type 1 infection of natural killer cell-deficient mice

Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts

Role of antibodies in controlling viral disease: lessons from experiments of nature and gene knockouts.

Fatal disseminated mouse adenovirus type 1 infection in mice lacking B cells or Bruton's tyrosine kinase.

Mouse adenovirus type 1 causes a fatal hemorrhagic encephalomyelitis in adult C57BL/6 but not BALB/c mice

Regulation of virus neutralization and the persistent fraction by TRIM21.

AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization.

P304

12397-12401

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1301918110

http://www.w3.org/2001/XMLSchema#string

P407

P433

30

http://www.w3.org/2001/XMLSchema#string

P478

110

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-07-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

248384735

http://www.w3.org/2001/XMLSchema#string

P698

23840060

http://www.w3.org/2001/XMLSchema#string

P921

P932

3725055

http://www.w3.org/2001/XMLSchema#string