Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins.
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Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparumImmune Escape Strategies of Malaria ParasitesHigh-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinationsNovel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screeningChemical interrogation of the malaria kinome.Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection.In vitro alterations do not reflect a requirement for host cell cycle progression during Plasmodium liver stage infection.Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery.Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria.Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei SporozoitesAn assay to probe Plasmodium falciparum growth, transmission stage formation and early gametocyte developmentThe cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.Assessment of dual life stage antiplasmodial activity of british seaweedsThe rodent malaria liver stage survives in the rapamycin-induced autophagosome of infected Hepa1-6 cellsChemical signatures and new drug targets for gametocytocidal drug development.New insight-guided approaches to detect, cure, prevent and eliminate malaria.Protein trafficking in apicomplexan parasites: crossing the vacuolar Rubicon.Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development.Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.A single rapamycin dose protects against late-stage experimental cerebral malaria via modulation of host immunity, endothelial activation and parasite sequestration.Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes.Realistically, how far are we from a universal malaria drug?Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities.Drugs in Development for Malaria.
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Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 July 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@en
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@nl
type
label
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@en
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@nl
prefLabel
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@en
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@nl
P2093
P2860
P50
P356
P1476
Torins are potent antimalarial ...... ous vacuole membrane proteins.
@en
P2093
Jonathan D Herman-Ornelas
Kathrin Buchholz
Matthias Marti
Thomas Hänscheid
Wandy L Beatty
P2860
P304
P356
10.1073/PNAS.1306097110
P407
P50
P577
2013-07-08T00:00:00Z