Monitoring kidney safety in drug development: emerging technologies and their implications.

Monitoring kidney safety in drug development: emerging technologies and their implications.

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http://www.wikidata.org/entity/Q37050523
In situ mass spectrometry imaging and ex vivo characterization of renal crystalline deposits induced in multiple preclinical drug toxicology studiesMapping drug physico-chemical features to pathway activity reveals molecular networks linked to toxicity outcomeOmega-3 and renal function in older adults.Urinary microRNA-10a and microRNA-30d serve as novel, sensitive and specific biomarkers for kidney injuryIschemic kidney injury and mechanisms of tissue repair.Silencing of hypoxia-inducible factor-1α gene attenuated angiotensin II-induced renal injury in Sprague-Dawley rats.Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure.Immunoaffinity capillary electrophoresis as a powerful strategy for the quantification of low-abundance biomarkers, drugs, and metabolites in biological matrices.A rapid urine test for early detection of kidney injury.Kidney disease associated with plasma cell dyscrasiasEmergence of biomarkers in nephropharmacology.Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
P2860

Monitoring kidney safety in drug development: emerging technologies and their implications.

Item
http://www.wikidata.org/entity/Q37050523
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Monitoring kidney safety in dr ...... logies and their implications.
@en
Monitoring kidney safety in dr ...... logies and their implications.
@nl
type
label
Monitoring kidney safety in dr ...... logies and their implications.
@en
Monitoring kidney safety in dr ...... logies and their implications.
@nl
prefLabel
Monitoring kidney safety in dr ...... logies and their implications.
@en
Monitoring kidney safety in dr ...... logies and their implications.
@nl
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P2093
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P1433
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Monitoring kidney safety in dr ...... ologies and their implications
@en
P2093
P304
P31
P433
P478
P577
P698