The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
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Implications for health and disease in the genetic signature of the Ashkenazi Jewish populationChronic inflammatory systemic diseases: An evolutionary trade-off between acutely beneficial but chronically harmful programsAn African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.Adjusting for HLA-DRbeta1 in a genome-wide association analysis of rheumatoid arthritis and related biomarkers.Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population.Development of admixture mapping panels for African Americans from commercial high-density SNP arraysAssociations of alcohol use with radiographic disease progression in African Americans with recent-onset rheumatoid arthritis.Diagnostic value of anti-cyclic citrullinated peptides and association with HLA-DRB1 shared epitope alleles in African rheumatoid arthritis patients.Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)--positive rheumatoid arthritis in three Asian ethnic groupsAssociation of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis.A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans.Associations of cigarette smoking with rheumatoid arthritis in African Americans.Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.Radiographic severity of rheumatoid arthritis in African Americans: results from a multicenter observational study.HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues.Parity and HLA alleles in risk of rheumatoid arthritisCapitalizing on admixture in genome-wide association studies: a two-stage testing procedure and application to height in African-AmericansAnti-fibrillarin antibody in African American patients with systemic sclerosis: immunogenetics, clinical features, and survival analysis.Acquisition of the rheumatoid arthritis HLA shared epitope through microchimerismImpact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans.Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope.HLA-DRB1 shared epitope genotyping using the revised classification and its association with circulating autoantibodies, acute phase reactants, cytokines and clinical indices of disease activity in a cohort of South African rheumatoid arthritis patiThe role of genetic variants in CRP in radiographic severity in African Americans with early and established rheumatoid arthritisImproved ancestry inference using weights from external reference panels.Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.Pharmacogenetics of etanercept in rheumatoid arthritis.The phenotype and genotype of rheumatoid arthritis in the Democratic Republic of Congo.Racial and ethnic disparities in rheumatoid arthritis.Human leukocyte antigen polymorphisms and personalized medicine for rheumatoid arthritis.Human Leukocyte Antigen-Disease Associations in Rheumatoid Arthritis.Association study of human leukocyte antigen-DRB1 alleles with rheumatoid arthritis in south Tunisian patients.Effect of the human leukocyte antigen HLA-DRB1 and anti-cyclic citrullinated peptide on the outcome of rheumatoid arthritis patients.Rheumatoid arthritis in Senegal: a comparison between patients coming from rural and urban areas, in an urban tertiary health care center in Senegal.Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans.The HLA-DRB1 shared epitope in Caucasians with rheumatoid arthritis: a lesson learned from tic-tac-toe.Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated prHLA-DRB1 allele association with rheumatoid arthritis susceptibility and severity in Syria.Role of Human Leukocyte Antigens (HLA) in Autoimmune Diseases.HLA-DRB1 shared epitope alleles in patients with rheumatoid arthritis: relation to autoantibodies and disease severity in a south Indian population.
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The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
@en
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
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type
label
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
@en
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
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prefLabel
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
@en
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
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P2093
P2860
P50
P356
P1476
The HLA-DRB1 shared epitope is ...... gh European genetic admixture.
@en
P2093
Beth L Jonas
Dahliann Morrison
David Reich
Doyt L Conn
Edwin A Smith
Gary S Gilkeson
Graciela S Alarcón
Harshit Dwivedi
James M Kelley
L Kelly Vaughan
P2860
P304
P356
10.1002/ART.23166
P577
2008-02-01T00:00:00Z