Antibody diversification by somatic mutation: from Burnet onwards.
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Proper application of antibodies for immunohistochemical detection: antibody crimes and how to prevent themTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationThe interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombinationA coming-of-age story: activation-induced cytidine deaminase turns 10.Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVIDResurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-α antibody.Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitroLysine residue at position 22 of the AID protein regulates its class switch activity.The autoimmunity of primary biliary cirrhosis and the clonal selection theory.Tissue-specific expressed antibody variable gene repertoiresSplice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells.The Charcot Lecture | beating MS: a story of B cells, with twists and turnsSerum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients.Computer-aided antibody design.The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.A guide to the perplexed on the specificity of antibodies.Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes.Structure and function of immunoglobulinsGene expression profiling for discovery of novel targets in human traumatic brain injury.Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunitiesMolecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity.Ubiquitination events that regulate recombination of immunoglobulin Loci gene segments.It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity.Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.Systems serology: profiling vaccine induced humoral immunity against HIV.Benchmarking the performance of human antibody gene alignment utilities using a 454 sequence dataset.Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy.B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals.Evolution and immunity.Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.
P2860
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P2860
Antibody diversification by somatic mutation: from Burnet onwards.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 January 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Antibody diversification by somatic mutation: from Burnet onwards.
@en
Antibody diversification by somatic mutation: from Burnet onwards.
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type
label
Antibody diversification by somatic mutation: from Burnet onwards.
@en
Antibody diversification by somatic mutation: from Burnet onwards.
@nl
prefLabel
Antibody diversification by somatic mutation: from Burnet onwards.
@en
Antibody diversification by somatic mutation: from Burnet onwards.
@nl
P356
P1476
Antibody diversification by somatic mutation: from Burnet onwards.
@en
P2093
Michael S Neuberger
P304
P356
10.1038/SJ.ICB.7100160
P577
2008-01-08T00:00:00Z