TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta - Wikidata - awgldk - TriplyDB

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

http://www.wikidata.org/entity/Q37052635

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TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines Dlg5 interacts with the TGF-β receptor and promotes its degradation Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development Ubc13: the Lys63 ubiquitin chain building machine Inflammatory microenvironment contributes to epithelial-mesenchymal transition in gastric cancer Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition p38 MAPK Signaling in Osteoblast Differentiation Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions Epithelial-Mesenchymal Transition and Breast Cancer TGF-β signaling via TAK1 pathway: role in kidney fibrosis Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Molecular mechanisms of epithelial-mesenchymal transition Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo The p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migration Complexities of TGF-β targeted cancer therapy.Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1 TGF-β family signaling in stem cells Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism TAK1 is an essential regulator of BMP signalling in cartilage TGF-beta-induced epithelial to mesenchymal transition Non-Smad pathways in TGF-beta signaling CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness.The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma.Regulation of Ubiquitin Enzymes in the TGF-β Pathway.TGF-beta biology in mammary development and breast cancer.Transforming growth factor beta (TGF-beta) and inflammation in cancer.Mesenchymal stem cells recruited by active TGFβ contribute to osteogenic vascular calcification Mechanisms of the epithelial-mesenchymal transition by TGF-beta Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.The regulation of TGF-β/SMAD signaling by protein deubiquitination.TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

http://www.wikidata.org/entity/Q37052635

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on September 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

@en

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta.

@nl

type

label

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

@en

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta.

@nl

prefLabel

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

@en

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta.

@nl

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J.MOLCEL.2008.09.002

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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

@en

P2093

Chaoyang Jin

http://www.w3.org/2001/XMLSchema#string

Karoly Fatyol

http://www.w3.org/2001/XMLSchema#string

Motozo Yamashita

http://www.w3.org/2001/XMLSchema#string

Xiangchun Wang

http://www.w3.org/2001/XMLSchema#string

Zhenggang Liu

http://www.w3.org/2001/XMLSchema#string

P2860

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

TGFbeta signaling in growth control, cancer, and heritable disorders

X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

Mammalian MAP kinase signalling cascades

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

Smad transcription factors

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918-924

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scholarly article

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10.1016/J.MOLCEL.2008.09.002

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6

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31

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2008-09-01T00:00:00Z

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18922473

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2621323

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