Regulation of prolactin receptor levels and activity in breast cancer
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Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylationProlactin cooperates with loss of p53 to promote claudin-low mammary carcinomasEffects of prolactin on TSC2-null Eker rat cells and in pulmonary lymphangioleiomyomatosisProlactin receptor in primary hyperparathyroidism--expression, functionality and clinical correlations.Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferationCharacterization of ductal and lobular breast carcinomas using novel prolactin receptor isoform specific antibodiesImmunomodulatory effects of sex hormones: requirements for pregnancy and relevance in melanoma.Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells.Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer.Lactogens and estrogens in breast cancer chemoresistance.Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.Prolactin promotes mammary pathogenesis independently from cyclin D1.Seasonal Expression of Prolactin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus).Prolactin Promotes Breast Cancer Cell Migration through Actin Cytoskeleton Remodeling.Modeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.PAK1 translocates into nucleus in response to prolactin but not to estrogen.Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway.Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1.SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cellsImpaired turnover of prolactin receptor contributes to transformation of human breast cells.Human metastatic melanoma cell lines express high levels of growth hormone receptor and respond to GH treatment.Eliminative signaling by Janus kinases: role in the downregulation of associated receptors.Hypothesis: prolactin is tumorigenic to human breast: dispelling the myth that prolactin-induced mammary tumors are rodent-specific.Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy.New insights in prolactin: pathological implications.Amplification of the prolactin receptor gene in mammary lobular neoplasia.Breast cancer: the menacing face of Janus kinase.Mutations in the exon 10 of prolactin receptor gene change the egg production performance in Wanjiang white goose.Novel SNPs of the bovine PRLR gene associated with milk production traits.The prolactin receptor transactivation domain is associated with steroid hormone receptor expression and malignant progression of breast cancer.
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Regulation of prolactin receptor levels and activity in breast cancer
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 19 January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Regulation of prolactin receptor levels and activity in breast cancer
@en
Regulation of prolactin receptor levels and activity in breast cancer.
@nl
type
label
Regulation of prolactin receptor levels and activity in breast cancer
@en
Regulation of prolactin receptor levels and activity in breast cancer.
@nl
prefLabel
Regulation of prolactin receptor levels and activity in breast cancer
@en
Regulation of prolactin receptor levels and activity in breast cancer.
@nl
P2093
P2860
P1476
Regulation of prolactin receptor levels and activity in breast cancer
@en
P2093
B Varghese
G Swaminathan
P2860
P2888
P356
10.1007/S10911-008-9068-6
P577
2008-01-19T00:00:00Z