Improving tumor uptake and excretion kinetics of 99mTc-labeled cyclic arginine-glycine-aspartic (RGD) dimers with triglycine linkers
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Radiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple IntegrinsRadiolabeled cyclic RGD peptides as radiotracers for tumor imagingIntravascular targets for molecular contrast-enhanced ultrasound imagingApplication of (68)Ga-PRGD2 PET/CT for αvβ3-integrin imaging of myocardial infarction and stroke.Peptide-based probes for targeted molecular imaging.Peptides and peptide hormones for molecular imaging and disease diagnosisEvaluation of 111In-labeled cyclic RGD peptides: tetrameric not tetravalent2-Mercaptoacetylglycylglycyl (MAG2) as a bifunctional chelator for 99mTc-labeling of cyclic RGD dimers: effect of technetium chelate on tumor uptake and pharmacokineticsMolecular imaging of angiogenesis with SPECT.Impact of multiple negative charges on blood clearance and biodistribution characteristics of 99mTc-labeled dimeric cyclic RGD peptides(99m)Tc-3P-RGD2 micro-single-photon emission computed tomography/computed tomography provides a rational basis for integrin αvβ3-targeted therapy.FITC-conjugated cyclic RGD peptides as fluorescent probes for staining integrin αvβ3/αvβ5 in tumor tissues.Effects of the amino acid linkers on the melanoma-targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-MSH peptides.Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECTIntegrin targeted delivery of radiotherapeutics.64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria.Evaluation of In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability.Evaluation of 99mTc-labeled cyclic RGD dimers: impact of cyclic RGD peptides and 99mTc chelates on biological properties.Introduction of an 8-aminooctanoic acid linker enhances uptake of 99mTc-labeled lactam bridge-cyclized α-MSH peptide in melanomaOptical imaging of integrin alphavbeta3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers.Evaluation of K(HYNIC)(2) as a bifunctional chelator for (99m)Tc-labeling of small biomolecules.Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkersRadiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.Anti-tumor effect of integrin targeted (177)Lu-3PRGD2 and combined therapy with Endostar.(99m)Tc-Galacto-RGD2: a novel 99mTc-labeled cyclic RGD peptide dimer useful for tumor imaging.Triazine-based tool box for developing peptidic PET imaging probes: syntheses, microfluidic radiolabeling, and structure-activity evaluationRadiometallated peptides for molecular imaging and targeted therapy.Evaluation of 68Ga-labeled iNGR peptide with tumor-penetrating motif for microPET imaging of CD13-positive tumor xenografts.Comparison of biological properties of 99mTc-labeled cyclic RGD Peptide trimer and dimer useful as SPECT radiotracers for tumor imaging.Fast clearing RGD-based near-infrared fluorescent probes for in vivo tumor diagnosis.Spacer effects on in vivo properties of DOTA-conjugated dimeric [Tyr3]octreotate peptides synthesized by a "Cu(I)-click" and "sulfo-click" ligation method.Impact of bifunctional chelators on biological properties of 111In-labeled cyclic peptide RGD dimers.Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK.Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.Dual-drug RGD conjugates provide enhanced cytotoxicity to melanoma and non-small lung cancer cells.Molecular imaging of hepatic stellate cell activity by visualization of hepatic integrin αvβ3 expression with SPECT in rat.An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo
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P2860
Improving tumor uptake and excretion kinetics of 99mTc-labeled cyclic arginine-glycine-aspartic (RGD) dimers with triglycine linkers
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article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Improving tumor uptake and exc ...... dimers with triglycine linkers
@en
Improving tumor uptake and exc ...... clic arginine-glycine-aspartic
@nl
type
label
Improving tumor uptake and exc ...... dimers with triglycine linkers
@en
Improving tumor uptake and exc ...... clic arginine-glycine-aspartic
@nl
prefLabel
Improving tumor uptake and exc ...... dimers with triglycine linkers
@en
Improving tumor uptake and exc ...... clic arginine-glycine-aspartic
@nl
P2093
P2860
P356
P1476
Improving tumor uptake and exc ...... dimers with triglycine linkers
@en
P2093
Lijun Wang
Shizhen Zhai
Shuang Liu
Zhaofei Liu
P2860
P304
P356
10.1021/JM801134K
P407
P577
2008-12-01T00:00:00Z