Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation
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Mouse models of intestinal cancerHMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell nicheAn Inducible, Large-Intestine-Specific Transgenic Mouse Model for Colitis and Colitis-Induced Colon Cancer ResearchInducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis.Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian EpitheliumIdentification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma.Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1Paneth Cell in Adenomas of the Distal Colorectum Is Inversely Associated with Synchronous Advanced Adenoma and Carcinoma.Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors.Proper division plane orientation and mitotic progression together allow normal growth of maize.Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.Wnt Signaling and Colorectal Cancer.Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal TumorigenesisYAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis.Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis.Inflammation and Colorectal Cancer.Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition
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P2860
Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Sox9 induction, ectopic Paneth ...... nal biallelic Apc inactivation
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Sox9 induction, ectopic Paneth ...... al biallelic Apc inactivation.
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type
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Sox9 induction, ectopic Paneth ...... nal biallelic Apc inactivation
@en
Sox9 induction, ectopic Paneth ...... al biallelic Apc inactivation.
@nl
prefLabel
Sox9 induction, ectopic Paneth ...... nal biallelic Apc inactivation
@en
Sox9 induction, ectopic Paneth ...... al biallelic Apc inactivation.
@nl
P2093
P2860
P1476
Sox9 induction, ectopic Paneth ...... nal biallelic Apc inactivation
@en
P2093
Alexandra Wiese
Eric R Fearon
Evan Sands
Kathleen R Cho
Kazuhiro Sentani
Maranne Green
P2860
P304
P356
10.1016/J.AJPATH.2013.04.013
P407
P50
P577
2013-06-13T00:00:00Z