How genetically engineered mouse tumor models provide insights into human cancers
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Molecular biology of lung cancer: clinical implicationsVEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedsideFrom Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung CancersRebuilding cancer metastasis in the mouseTargeting and utilizing primary tumors as live vaccines: changing strategiesIn vitro and in vivo models for analysis of resistance to anticancer molecular therapiesA murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.Imaging tumor metabolism using positron emission tomographyA tree shrew glioblastoma model recapitulates features of human glioblastomaCross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.RAS pathway biomarkers for breast cancer prognosis.DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarizationMYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Optimizing mouse models for precision cancer prevention.Genetically engineered mouse models for drug development and preclinical trials.Advancing cancer drug discovery towards more agile development of targeted combination therapies.The nuclear envelope environment and its cancer connections.Alveolar type II cells possess the capability of initiating lung tumor developmentMouse Tumor Biology (MTB): a database of mouse models for human cancerModelling bladder cancer in mice: opportunities and challenges.Translating cancer 'omics' to improved outcomes.The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.The molecular classification of medulloblastoma: driving the next generation clinical trials.Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform.Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models.Genetically engineered cancer models, but not xenografts, faithfully predict anticancer drug exposure in melanoma tumors.Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response.Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis.Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer modelsNeutrophils: Critical components in experimental animal models of cancer.Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer.Andrographolide suppress tumor growth by inhibiting TLR4/NF-κB signaling activation in insulinomaGuidelines for preclinical and early phase clinical assessment of novel radiosensitisersDiscovery of small molecule cancer drugs: successes, challenges and opportunities.Challenges in the development of an autologous heat shock protein based anti-tumor vaccine.In vivo animal models for studying brain metastasis: value and limitations.Epidermal growth factor receptor tyrosine-kinase inhibitor treatment resistance in non-small cell lung cancer: biological basis and therapeutic strategies.Application of proteomics in the study of rodent models of cancer.Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
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How genetically engineered mouse tumor models provide insights into human cancers
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 January 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
How genetically engineered mouse tumor models provide insights into human cancers
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How genetically engineered mouse tumor models provide insights into human cancers.
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type
label
How genetically engineered mouse tumor models provide insights into human cancers
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How genetically engineered mouse tumor models provide insights into human cancers.
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prefLabel
How genetically engineered mouse tumor models provide insights into human cancers
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How genetically engineered mouse tumor models provide insights into human cancers.
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P2860
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P1476
How genetically engineered mouse tumor models provide insights into human cancers
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P2860
P304
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10.1200/JCO.2010.30.8304
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P577
2011-01-24T00:00:00Z