Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
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Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug useAlternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expressionTransgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice.Genetic influences on response to alcohol and response to pharmacotherapies for alcoholism.CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.Human and laboratory rodent low response to alcohol: is better consilience possible?Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence.Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats.Evaluating a cognitive model of ALDH2 and drinking behavior.The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental areaA novel cholinergic action of alcohol and the development of tolerance to that effect in Caenorhabditis elegans.Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry.Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior.Pharmacological stress is required for the anti-alcohol effect of the α3β4* nAChR partial agonist AT-1001Linkage analyses of stimulant dependence, craving, and heavy use in American Indians.fMRI differences between subjects with low and high responses to alcohol during a stop signal taskA brief history of research on the genetics of alcohol and other drug use disorders.Glypican Gene GPC5 Participates in the Behavioral Response to Ethanol: Evidence from Humans, Mice, and Fruit FliesRecent advances in the genetic epidemiology and molecular genetics of substance use disorders.Endophenotypes for Alcohol Use Disorder: An Update on the Field.Nicotinic Mechanisms Modulate Ethanol Withdrawal and Modify Time Course and Symptoms Severity of Simultaneous Withdrawal from Alcohol and Nicotine.A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine.No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors.Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.Acute ethanol effects on brain activation in low- and high-level responders to alcohol.Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders.The α5 neuronal nicotinic acetylcholine receptor subunit plays an important role in the sedative effects of ethanol but does not modulate consumption in mice.Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions.Nicotine administration in the cholinergic basal forebrain increases alcohol consumption in C57BL/6J mice.The CHRNA5-A3-B4 gene cluster in nicotine addiction.Common single nucleotide variants underlying drug addiction: more than a decade of research.Subjective Response to Alcohol as a Research Domain Criterion.Experimental psychopathology paradigms for alcohol use disorders: Applications for translational researchExamination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study.A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems.Neural and psychological characteristics of college students with alcoholic parents differ depending on current alcohol use.Nicotine administration in the wake-promoting basal forebrain attenuates sleep-promoting effects of alcohol.Nicotinic acetylcholine receptor (CHRN) expression and function in cultured human adult fungiform (HBO) taste cells.Genetics of alcohol dependence
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Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
@en
Chromosome 15q25.1 genetic mar ...... response to alcohol in humans.
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type
label
Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
@en
Chromosome 15q25.1 genetic mar ...... response to alcohol in humans.
@nl
prefLabel
Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
@en
Chromosome 15q25.1 genetic mar ...... response to alcohol in humans.
@nl
P2093
P2860
P356
P1476
Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans
@en
P2093
Geoff Joslyn
Gerry Brush
Jelger Kalmijn
Margaret Robertson
Raymond L White
Tom L Smith
P2860
P304
20368-20373
P356
10.1073/PNAS.0810970105
P407
P577
2008-12-08T00:00:00Z