Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
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Neuroprotective mechanisms of the ACE2-angiotensin-(1-7)-Mas axis in strokeUpregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.Oral delivery of Angiotensin-converting enzyme 2 and Angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension.Update in pulmonary vascular diseases 2013.Angiotensin-converting enzyme 2 (ACE2) activator diminazene aceturate ameliorates endotoxin-induced uveitis in miceNeuroinflammation in pulmonary hypertension: concept, facts, and relevance.Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysmsShort-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy.Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.ACE2 and Microbiota: Emerging Targets for Cardiopulmonary Disease TherapyDiminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease.ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.Angiotensin-converting enzyme 2 activator diminazene aceturate prevents lipopolysaccharide-induced inflammation by inhibiting MAPK and NF-κB pathways in human retinal pigment epithelium.Angiotensin converting enzyme versus angiotensin converting enzyme-2 selectivity of MLN-4760 and DX600 in human and murine bone marrow-derived cells.Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.Diminazene aceturate improves autonomic modulation in pulmonary hypertensionRole of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart FailureNew agents modulating the renin-angiotensin-aldosterone system-Will there be a new therapeutic option?Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitroEndothelial cell regulation of pulmonary vascular tone, inflammation, and coagulation.Future drug discovery in renin-angiotensin-aldosterone system intervention.Endothelial dysfunction and vascular disease - a 30th anniversary update.The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases.Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice.Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology.Activation of angiotensin-converting enzyme 2 improves cardiac electrical changes in ventricular repolarization in streptozotocin-induced hyperglycaemic rats.Beneficial Effects Of Angiotensin-(1-7) On Cd34 + Cells From Heart Failure Patients.Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.ACE2-angiotensin-(1-7)-Mas axis might be a promising therapeutic target for pulmonary arterial hypertension.The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury.A novel ACE2 activator reduces monocrotaline-induced pulmonary hypertension by suppressing the JAK/STAT and TGF-β cascades with restored caveolin-1 expression.rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling.The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice
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Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 January 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Diminazene attenuates pulmonar ...... ctions in experimental models.
@en
Diminazene attenuates pulmonar ...... ctions in experimental models.
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type
label
Diminazene attenuates pulmonar ...... ctions in experimental models.
@en
Diminazene attenuates pulmonar ...... ctions in experimental models.
@nl
prefLabel
Diminazene attenuates pulmonar ...... ctions in experimental models.
@en
Diminazene attenuates pulmonar ...... ctions in experimental models.
@nl
P2093
P2860
P50
P1476
Diminazene attenuates pulmonar ...... nctions in experimental models
@en
P2093
Altin Gjymishka
Anderson J Ferreira
Arturo J Cardounel
Chastity Bradford
Deepmala Agarwal
Dipankar Gupta
Erin Bruce
Jane Yellowlees Douglas
Jawaharlal M Patel
P2860
P304
P356
10.1164/RCCM.201205-0880OC
P407
P577
2013-01-31T00:00:00Z