Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30
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Molecular determinants of influenza virus pathogenesis in mice.Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 virusesIdentification of PB2 mutations responsible for the efficient replication of H5N1 influenza viruses in human lung epithelial cellsMammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus.Appearance of L90I and N205S Mutations in Effector Domain of NS1 Gene of pdm (09) H1N1 Virus from India during 2009-2013.A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes.Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expressionEvidence-based translation for the genomic responses of murine models for the study of human immunity.Fluorescence-Activated Cell Sorting-Based Analysis Reveals an Asymmetric Induction of Interferon-Stimulated Genes in Response to Seasonal Influenza A VirusStructural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.Interferon Lambda: Modulating Immunity in Infectious Diseases.Deep sequencing reveals the eight facets of the influenza A/HongKong/1/1968 (H3N2) virus cap-snatching process.The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site During Circulation in Humans.H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?Isolation and full genome characterization of avian influenza subtype H9N2 from poultry respiratory disease outbreak in Egypt.The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1.NS Segment of a 1918 Influenza A Virus-Descendent Enhances Replication of H1N1pdm09 and Virus-Induced Cellular Immune Response in Mammalian and Avian Systems.Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compoundsZoonotic Potential of Influenza A Viruses: A Comprehensive Overview
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Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 25 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Influenza A/Hong Kong/156/1997 ...... in binding to RIG-I and CPSF30
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Influenza A/Hong Kong/156/1997 ...... n binding to RIG-I and CPSF30.
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type
label
Influenza A/Hong Kong/156/1997 ...... in binding to RIG-I and CPSF30
@en
Influenza A/Hong Kong/156/1997 ...... n binding to RIG-I and CPSF30.
@nl
prefLabel
Influenza A/Hong Kong/156/1997 ...... in binding to RIG-I and CPSF30
@en
Influenza A/Hong Kong/156/1997 ...... n binding to RIG-I and CPSF30.
@nl
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P50
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Influenza A/Hong Kong/156/1997 ...... in binding to RIG-I and CPSF30
@en
P2093
Earl G Brown
Elena Miranda
Jianjun Jia
Jihui Ping
Martin Pelchat
Samar K Dankar
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P356
10.1186/1743-422X-10-243
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2013-07-25T00:00:00Z