Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. - Wikidata - awgldk - TriplyDB

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.

http://www.wikidata.org/entity/Q37070610

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Inflammasomes: too big to miss The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles The Relationship between NALP3 and Autoinflammatory Syndromes Improving the clinical impact of biomaterials in cancer immunotherapy.Molecular mechanisms regulating NLRP3 inflammasome activation Choice and Design of Adjuvants for Parenteral and Mucosal Vaccines Lighting the fires within: the cell biology of autoinflammatory diseases Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing Structure of RiVax: a recombinant ricin vaccine Adjuvants for peptide-based cancer vaccines International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Synthetic Nanoparticles for Vaccines and Immunotherapy NLRP3 inflammasome activation induced by engineered nanomaterials Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.Protective immunity to influenza: lessons from the virus for successful vaccine design.NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity.Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice.Application of nanotechnologies for improved immune response against infectious diseases in the developing world Effective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2.Recent progress in adjuvant discovery for peptide-based subunit vaccines Toll-like receptor agonists: are they good adjuvants?Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptors Wound Healing Versus Regeneration: Role of the Tissue Environment in Regenerative Medicine.The role of integrins in the recognition and response of dendritic cells to biomaterials Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen Exposure to titanium dioxide nanomaterials provokes inflammation of an in vitro human immune construct.Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles.Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.Biodegradable microparticles loaded with doxorubicin and CpG ODN for in situ immunization against cancer.Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen.

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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.

http://www.wikidata.org/entity/Q37070610

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 12 January 2009

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@en

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@nl

type

label

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@en

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@nl

prefLabel

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@en

Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

@nl

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PNAS.0804897106

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Proceedings of the National Academy of Sciences of the United States of America

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Uptake of particulate vaccine ...... ivates the NALP3 inflammasome.

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Benjamin Claass

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Darren Ruane

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Derek T O'Hagan

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Fiona A Sharp

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Luke A J O'Neill

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Manomohan Singh

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Padma Malyala

http://www.w3.org/2001/XMLSchema#string

P2860

NLRs join TLRs as innate sensors of pathogens

Active caspase-1 is a regulator of unconventional protein secretion

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

Gout-associated uric acid crystals activate the NALP3 inflammasome

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

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870-875

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10.1073/PNAS.0804897106

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106

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Virginie Pétrilli

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2009-01-12T00:00:00Z

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23782644

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19139407

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2630092

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