Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype.

Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype.

Item
http://www.wikidata.org/entity/Q37072132
Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeresTelomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scramblingTelomeric recombination induced by dysfunctional telomeres.Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cellsRecombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity.Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification.Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts.Telomeres and telomerase in Candida albicans.Rap1 in Candida albicans: an unusual structural organization and a critical function in suppressing telomere recombination.The many facets of homologous recombination at telomeres.Taking apart Rap1: an adaptor protein with telomeric and non-telomeric functions
P2860

Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype.

Item
http://www.wikidata.org/entity/Q37072132
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@en
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@nl
type
label
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@en
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@nl
prefLabel
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@en
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Mutant telomeric repeats in ye ...... g of telomeres-like phenotype.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932