Hsp90 inhibitor partially corrects nephrogenic diabetes insipidus in a conditional knock-in mouse model of aquaporin-2 mutation.
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A novel therapeutic effect of statins on nephrogenic diabetes insipidusProtein trafficking defects in inherited kidney diseasesDistinct roles of molecular chaperones HSP90α and HSP90β in the biogenesis of KCNQ4 channelsRole of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complexAquaporins: important but elusive drug targets.Aquaporins in clinical medicine.Regulation of transport in the connecting tubule and cortical collecting ductNephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment.Functional polymorphisms affecting the clinically important arginine-137 residue of AVPR2 do not influence serum sodium concentration at the population levelImpaired surface expression and conductance of the KCNQ4 channel lead to sensorineural hearing lossAKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.Aquaporins: translating bench research to human disease.Ion channelopathies in endocrinology: recent genetic findings and pathophysiological insights.Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.Congenital nephrogenic diabetes insipidus: the current state of affairs.Virtual prototyping study shows increased ATPase activity of Hsp90 to be the key determinant of cancer phenotype.The AQP2 mutation V71M causes nephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog.Hereditary Nephrogenic Diabetes Insipidus: Pathophysiology and Possible Treatment. An Update.Diabetes Insipidus.Aquaporins in Urinary System.Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases.Generation and analyses of R8L barttin knockin mouse
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Hsp90 inhibitor partially corrects nephrogenic diabetes insipidus in a conditional knock-in mouse model of aquaporin-2 mutation.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@en
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@nl
type
label
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@en
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@nl
prefLabel
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@en
Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@nl
P2093
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P356
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Hsp90 inhibitor partially corr ...... model of aquaporin-2 mutation.
@en
P2093
A S Verkman
Baoxue Yang
P2860
P304
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10.1096/FJ.08-118422
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P577
2008-10-14T00:00:00Z