about
Supramolecular coordination: self-assembly of finite two- and three-dimensional ensemblesSolution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic SequenceFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNAThe crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceCobalt(III)porphyrin to target G-quadruplex DNA.A comparison of four different conformations adopted by human telomeric G-Quadruplex using Computer Simulations.Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNAChemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeatsSynthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties.Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.G-quadruplexes in viruses: function and potential therapeutic applications.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Existence of G-quadruplex structures in promoter region of oncogenes confirmed by G-quadruplex DNA cross-linking strategy.Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity.Small molecules targeting c-Myc oncogene: promising anti-cancer therapeuticsThe nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells.A mRNA-Responsive G-Quadruplex-Based Drug Release SystemThe interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids.Discovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression.Combining a Ru(II) "Building Block" and Rapid Screening Approach to Identify DNA Structure-Selective "Light Switch" Compounds.Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol.Ruthenium Complex "Light Switches" that are Selective for Different G-Quadruplex Structures.Specific recognition and stabilization of monomeric and multimeric G-quadruplexes by cationic porphyrin TMPipEOPP under molecular crowding conditionsG-register exchange dynamics in guanine quadruplexes.A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoterPreparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor ActivityDiscovery of new G-quadruplex binding chemotypes.Interaction of metal complexes with G-quadruplex DNA.G-quadruplexes-novel mediators of gene function.Mass spectrometry of G-quadruplex DNA: formation, recognition, property, conversion, and conformation.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Chemical architecture and applications of nucleic acid derivatives containing 1,2,3-triazole functionalities synthesized via click chemistry.Fluorescent probes for G-quadruplex structures.DNA G-quadruplex binders: a patent review.G-quadruplexes as potential therapeutic targets for embryonal tumors.Macrocyclic polyoxazoles as G-quadruplex ligands.
P2860
Q27010271-BC60B218-9BD4-46FA-96AA-9F5CA8FB1E00Q27659789-DBE977C1-1888-4087-B736-AB3B9AC73CB9Q27666501-D4FD6AD8-3220-466D-BF7C-5E79C8A95F70Q27674766-5628D6B5-F8BA-4542-8270-6F4AB2F34583Q27680131-2DC8CC70-6248-41C1-A1B4-44157E9995A7Q30883701-FF1DA1F0-08C3-47EA-AC1E-7EAF5A2E7F5AQ31003157-CFB20A00-E358-4AD6-A8F4-EB1EE8DFE5C3Q33566519-76AAA594-5ECF-4C6F-9D8F-253488577348Q33814333-2BCDB770-BE18-44FE-A3CA-59C03AC018A0Q33924776-E51A77FF-6A18-46E5-AD43-4ED27C119C70Q34026449-853D7002-0A55-4233-A229-ADE93D35C47FQ34097355-1DCE406B-B67C-4605-BB6C-C6C1D4A1C74CQ34341191-F7EE6D89-0C30-4D1C-A926-50F1FBCC29ACQ34413414-F3D02E91-082C-4990-BD3F-610F53FC2237Q34489819-8A0EAC5A-8F6E-4B43-A4C3-FB7B7E61FFB3Q34559605-7BEAEA1D-E45C-4539-B765-F40FD3EDAD22Q34711479-7DE7FA2F-4E45-4592-9CDD-4AF1BF49CEB9Q34981675-E73F94CB-E32B-4F6A-8182-D25498A70996Q35353405-DDD07F08-689C-4344-93C3-2A4DE018EF8BQ35595663-D68A7316-1AF4-4F19-A0A2-B62016F28BCBQ35605050-F926D788-02CC-455F-9908-CF846A05BAF3Q35866171-74F60D27-105F-4E40-88AB-82BAA900B0BAQ36110185-4065F81F-8574-4B30-A4AD-1B035BE2644CQ36234500-B83FF26E-94DB-4D96-841E-8605A503BB98Q36280620-075266E8-334B-4D31-A53A-730D0F26EE9FQ36437082-33415A36-0AD9-45E7-B970-9E38EBE35376Q36769506-10643D99-BC39-4219-A46C-2551317307D0Q36870535-9A79C2EA-6259-4FC7-AAFC-A3C06964E821Q37216613-3214C2B1-FA6E-4F75-8155-1C91902A3F77Q37450636-05D29808-81CD-4AD1-9BB3-4254781571EAQ37511907-A14212A1-A6F2-458B-A3A5-6375424E42F0Q37760871-25509531-B4CF-4CD9-9246-C4F04F06498CQ37837700-7EA1F1BC-3800-4BB9-B0AB-7E17E7DC31C7Q37869046-B5E6B81F-D3F3-4A2C-80A1-7CABE7C071C2Q37905612-A8897B7F-43E0-4B6C-A6E3-EB0C7BCB430AQ38056000-1109B338-53D8-46DB-9305-A5AC4FC3E70CQ38084623-A7F228D1-6BF5-4D69-94D7-5900B422B80EQ38131073-3D7A84A4-31E6-4D3B-96BC-9A43872AEA97Q38154988-19D85891-5B7B-4229-AE54-35081A914A3DQ38172052-A9CD9620-75F0-4615-960D-4F26B5F61A0A
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
G-quadruplexes: targets in anticancer drug design.
@en
G-quadruplexes: targets in anticancer drug design.
@nl
type
label
G-quadruplexes: targets in anticancer drug design.
@en
G-quadruplexes: targets in anticancer drug design.
@nl
prefLabel
G-quadruplexes: targets in anticancer drug design.
@en
G-quadruplexes: targets in anticancer drug design.
@nl
P2093
P356
P1433
P1476
G-quadruplexes: targets in anticancer drug design
@en
P2093
Jia-heng Tan
Lian-quan Gu
Tian-miao Ou
Yu-jing Lu
Zhi-shu Huang
P2860
P304
P356
10.1002/CMDC.200700300
P577
2008-05-01T00:00:00Z