Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model. - Wikidata - awgldk - TriplyDB

Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.

Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.

http://www.wikidata.org/entity/Q37075399

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Withaferin-A--A Natural Anticancer Agent with Pleitropic Mechanisms of Action Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Broad targeting of angiogenesis for cancer prevention and therapy Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors.Mammary cancer chemoprevention by withaferin A is accompanied by in vivo suppression of self-renewal of cancer stem cells Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.Short-form RON overexpression augments benzyl isothiocyanate-induced apoptosis in human breast cancer cells Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown.Withania somnifera: From prevention to treatment of cancer Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide.Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells Pharmacologic overview of Withania somnifera, the Indian Ginseng.Withaferin A suppresses the up-regulation of acetyl-coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model.Natural Withanolides in the Treatment of Chronic Diseases.Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants.Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancer Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A.Towards natural mimetics of metformin and rapamycin.Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate.Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.

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Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.

http://www.wikidata.org/entity/Q37075399

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Metabolic alterations in mamma ...... inically relevant mouse model.

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Journal of the National Cancer Institute

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Metabolic alterations in mamma ...... inically relevant mouse model.

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Anuradha Sehrawat

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Eun-Ryeong Hahm

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Joomin Lee

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Julie A Arlotti

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Rohit Bhargava

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Shivendra V Singh

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Sruti S Shiva

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Su-Hyeong Kim

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P2860

PCNA and Ki67 expression in breast carcinoma: correlations with clinical and biological variables

Cancer statistics, 2010

Tumor angiogenesis: therapeutic implications

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

On the Origin of Cancer Cells

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer.

Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect.

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1111-1122

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scholarly article

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10.1093/JNCI/DJT153

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15

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105

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2013-07-02T00:00:00Z

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244992803

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23821767

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