ZEB1 links p63 and p73 in a novel neuronal survival pathway rapidly induced in response to cortical ischemia.
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Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivityThe ZEB1 transcription factor is a novel repressor of adiposity in female micemiR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in miceCerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.Repression of Zeb1 and hypoxia cause sequential mesenchymal-to-epithelial transition and induction of aid, Oct4, and Dnmt1, leading to immortalization and multipotential reprogramming of fibroblasts in spheresmiR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition.Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons.Delayed hippocampal neuronal death in young gerbil following transient global cerebral ischemia is related to higher and longer-term expression of p63 in the ischemic hippocampus.Mammary epithelial cell polarity is regulated differentially by p73 isoforms via epithelial-to-mesenchymal transition.Profiling of Signaling Proteins in Penumbra After Focal Photothrombotic Infarct in the Rat Brain Cortex.Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63.Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor.Evolutionary functional analysis and molecular regulation of the ZEB transcription factors.ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer.EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.Expanding roles of ZEB factors in tumorigenesis and tumor progression.Twist predicts poor outcome of patients with astrocytic glioma.Physiologic Reelin does not play a strong role in protection against acute stroke.p73 gene in dopaminergic neurons is highly susceptible to manganese neurotoxicity.Zfh1 promotes survival of a peripheral glia subtype by antagonizing a Jun N-terminal kinase-dependent apoptotic pathway.Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP.
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ZEB1 links p63 and p73 in a novel neuronal survival pathway rapidly induced in response to cortical ischemia.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@en
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
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type
label
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@en
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@nl
prefLabel
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@en
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@nl
P2093
P2860
P1433
P1476
ZEB1 links p63 and p73 in a no ...... response to cortical ischemia.
@en
P2093
Augusto Sola
Hisato Kondoh
Judith Sequeira
Tom Genetta
Tong Chun Wen
Yujiro Higashi
P2860
P356
10.1371/JOURNAL.PONE.0004373
P407
P577
2009-02-04T00:00:00Z