Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria.
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Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malariaeditThe effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient dataPharmacokinetic and pharmacodynamic considerations in antimalarial dose optimizationMaking the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugsMathematical Modelling to Guide Drug Development for Malaria EliminationEfficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium vivax malaria in endemic countries: meta-analysis of randomized controlled studiesProtective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trialEfficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquinePopulation Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan childrenPopulation pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling.Randomized comparison of the efficacies and tolerabilities of three artemisinin-based combination treatments for children with acute Plasmodium falciparum malaria in the Democratic Republic of the Congo.Population Pharmacokinetics and Antimalarial Pharmacodynamics of Piperaquine in Patients With Plasmodium vivax Malaria in ThailandInterspecies allometric scaling of antimalarial drugs and potential application to pediatric dosing.Effect of coadministered fat on the tolerability, safety, and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria.Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study.Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis.Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challengesPharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infantsArtemisinin combination therapy: a good antimalarial, but is the dose right?Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the setting of three different chemopreventive regimens.Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination.The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a systematic review and pooled analysis of individual patient data.Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial.Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical AssessmentRandomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina FasoRethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study.Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malariaVariable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children.Characterization of the infectious reservoir of malaria with an agent-based model calibrated to age-stratified parasite densities and infectiousnessEfficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern LaosTreatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim(®)) in the treatment of uncomplicated malaria at public health facilities in four African countries.A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria.Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study.Population pharmacokinetics of intramuscular artesunate in African children with severe malaria: implications for a practical dosing regimen.Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients.Population Pharmacokinetics of Piperaquine in Young Ugandan Children Treated With Dihydroartemisinin-Piperaquine for Uncomplicated Malaria.
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Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 January 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Population pharmacokinetics an ...... omplicated falciparum malaria.
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Population pharmacokinetics an ...... omplicated falciparum malaria.
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type
label
Population pharmacokinetics an ...... omplicated falciparum malaria.
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Population pharmacokinetics an ...... omplicated falciparum malaria.
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Population pharmacokinetics an ...... omplicated falciparum malaria.
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Population pharmacokinetics an ...... omplicated falciparum malaria.
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P1476
Population pharmacokinetics an ...... omplicated falciparum malaria.
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J-B Ouedraogo
N Lindegardh
P J Rosenthal
W Hanpithakpong
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P304
P356
10.1038/CLPT.2011.254
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P577
2012-01-18T00:00:00Z