Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
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Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic SignalingThe Role of Hedgehog Signaling in Tumor Induced Bone DiseaseCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyThe many faces of neuroendocrine differentiation in prostate cancer progressionParacrine sonic hedgehog signaling contributes significantly to acquired steroidogenesis in the prostate tumor microenvironmentEffects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cellsHedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent stateMolecular pathways and targets in prostate cancerA new role for Hedgehogs in juxtacrine signaling.Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse modelGli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines.Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts.GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.The hedgehog/Gli signaling paradigm in prostate cancerHedgehog signaling in prostate epithelial-mesenchymal growth regulation.Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells.Hedgehog signaling in prostate cancer and its therapeutic implicationInhibition of hedgehog and androgen receptor signaling pathways produced synergistic suppression of castration-resistant prostate cancer progression.Integrated Hedgehog signaling is induced following castration in human and murine prostate cancers.NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer.The utility of hedgehog signaling pathway inhibition for cancer.Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling.Sonic hedgehog and androgen signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer.TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling.Cross modulation between the androgen receptor axis and protocadherin-PC in mediating neuroendocrine transdifferentiation and therapeutic resistance of prostate cancer.Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer.Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer.Paracrine Hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner.Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3.Global gene expression profiling and tissue microarray reveal novel candidate genes and down-regulation of the tumor suppressor gene CAV1 in sporadic vestibular schwannomas.Hedgehog signalling pathway inhibitors as cancer suppressing agentsAndrogen receptor activation results in metabolite signatures of an aggressive prostate cancer phenotype: an NMR-based metabonomics study
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P2860
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@en
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@nl
type
label
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@en
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@nl
prefLabel
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@en
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells
@en
P2093
Alice C Levine
Elina Levina
Mengqian Chen
Patrice Ohouo
Ralph Buttyan
P2860
P304
P356
10.4161/CC.8.1.7532
P577
2009-01-01T00:00:00Z