An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
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New insights into the role of RNase L in innate immunityThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseReduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis.Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection.Enteropathogenic Escherichia coli inhibits type I interferon- and RNase L-mediated host defense to disrupt intestinal epithelial cell barrier functionInterferon-inducible effector mechanisms in cell-autonomous immunity.Expression, purification and characterization of the interferon-inducible, antiviral and tumour-suppressor protein, human RNase L.Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogensRNase L interacts with Filamin A to regulate actin dynamics and barrier function for viral entryRNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative responseHost-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection.Lack of RNase L attenuates macrophage functionsRibonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs.Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesteraseRNase L triggers autophagy in response to viral infections.Pathologic effects of RNase-L dysregulation in immunity and proliferative control.Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome.Regulation of human RNase-L by the miR-29 family reveals a novel oncogenic role in chronic myelogenous leukemiaRNase-L deficiency exacerbates experimental colitis and colitis-associated cancer.Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people.RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting.The effect of combination IFN-alpha-2a with usual antituberculosis chemotherapy in non-responding tuberculosis and diabetes mellitus: a case report and review of the literature.Recognition of 2',5'-linked oligoadenylates by human ribonuclease L: molecular dynamics study.Rapid RNase L-Driven Arrest of Protein Synthesis in the dsRNA Response without Degradation of Translation Machinery.The Roles of Type I Interferon in Bacterial Infection.Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells.Curcumin, a natural antioxidant, acts as a noncompetitive inhibitor of human RNase L in presence of its cofactor 2-5A in vitro.Protection of macrophages from intracellular pathogens by miR-182-5p mimic-a gene expression meta-analysis approach.
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An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@en
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@nl
type
label
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@en
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@nl
prefLabel
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@en
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
@nl
P2093
P2860
P356
P1476
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity
@en
P2093
Alan S Cross
Bret A Hassel
Heather J Ezelle
Janette Harro
Jeffrey D Hasday
Kari Ann Shirey
Oswald R Crasta
Stefanie N Vogel
Tae-Jin Kang
P2860
P304
20816-20821
P356
10.1073/PNAS.0807265105
P407
P577
2008-12-15T00:00:00Z