The melanocortin 1 receptor and the UV response of human melanocytes--a shift in paradigm.
about
The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humansMelanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism.Zebrafish have a competent p53-dependent nucleotide excision repair pathway to resolve ultraviolet B-induced DNA damage in the skin.Networks and pathways in pigmentation, health, and disease.Malignant melanoma and melanocortin 1 receptor.Melanoma molecular subtypes: unifying and paradoxical results.Key role of CRF in the skin stress response system.Updates of reactive oxygen species in melanoma etiology and progression.Two-photon excited fluorescence lifetime imaging and spectroscopy of melanins in vitro and in vivoMelanocortin MC₁ receptor in human genetics and model systems.Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulationBenefits of oral Polypodium Leucotomos extract in MM high-risk patientsPigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation.Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas populationMicroarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1rForskolin protects keratinocytes from UVB-induced apoptosis and increases DNA repair independent of its effects on melanogenesis.Is Mc1r an important regulator of non-pigmentary responses to UV radiation?Pharmacologic induction of epidermal melanin and protection against sunburn in a humanized mouse model.Prognostic significance of melanoma differentiation and trans-differentiationPheomelanin-induced oxidative stress: bright and dark chemistry bridging red hair phenotype and melanoma.MicroRNAs in melanocyte and melanoma biology.Afamelanotide: A Review in Erythropoietic Protoporphyria.The colours of humanity: the evolution of pigmentation in the human lineage.The melanocortin signaling cAMP axis accelerates repair and reduces mutagenesis of platinum-induced DNA damage.Semi-rigid tripeptide agonists of melanocortin receptors.Purification and growth of melanocortin 1 receptor (Mc1r)- defective primary murine melanocytes is dependent on stem cell factor (SFC) from keratinocyte-conditioned media.Amyloids, melanins and oxidative stress in melanomagenesis.The mathematics of tanningEnhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR.Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases.Linking αMSH with PPARγ in B16-F10 melanoma.The effect of MC1R variants and sunscreen on the response of human melanocytes in vivo to ultraviolet radiation and implications for melanoma.Palmitoylation-dependent activation of MC1R prevents melanomagenesis.Design of MC1R Selective γ-MSH Analogues with Canonical Amino Acids Leads to Potency and Pigmentation.MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas.MC1R stimulation by alpha-MSH induces catalase and promotes its re-distribution to the cell periphery and dendrites.Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentation.
P2860
Q33529045-E7FA20BA-8498-4C95-A9E0-1C13F2070727Q33554134-FFDAF50D-7BF0-4332-B564-D9BB2CC5CFCDQ33584237-59EA4AE5-1802-4FF2-B748-EBA45127C0C5Q33584524-CF1FE6A0-C390-41E1-A218-48D4351F23BEQ33782773-A36505BA-0F85-4A9B-9519-9A12F5D92971Q34179210-AA9BAF1B-F692-45CF-8524-D4658E532679Q34363640-A8C12722-CD50-4B94-8176-5BA7F2EDFC4EQ34403921-8814BC1A-E6E8-43FF-845B-D5DBF9068999Q34510012-B93C5510-CD4B-4096-AF0E-86E43BB221E0Q34984641-BDB0250A-25D4-4C88-B498-20912BCA75DBQ35129901-F035E925-20D1-431B-BD46-5F8AE70F80C0Q36015428-F92BC1AA-FA4A-4C09-9412-65F10C3506F1Q36347347-59BE6E56-8FE6-4D08-A73E-450F5B25ED55Q37040909-7427A86D-7002-4C09-B696-58B405975569Q37100856-5298C76F-CE09-42A9-8F2E-34E6EE3F2E20Q37125731-D6E6A4BA-15DC-4E72-AC3B-D0161DE668FDQ37352789-242ADC23-641B-4B3A-9AD6-7C11969E4EA4Q37380135-6BA26F5C-4B51-48F5-AF31-DD0B7FCCC8B7Q38006471-919E5017-7CBE-46A5-98BF-B42E98223901Q38210674-E1F09A99-EA73-4A09-8C03-EEB9DDAF0AF7Q38291001-EA86475B-4BE7-4335-8026-9B4B893539A4Q38775733-75D44953-563E-4774-AB45-C00E66C76C97Q39097633-C9782F59-6C99-41B7-95FC-A4BD2B402DFFQ41718210-4F59BAFF-444E-428F-B75C-7D832509440CQ41962062-A0F9B2C1-C058-407B-B2E6-2BA0A0EEDF0AQ41982019-83F3CD57-D6FE-4186-BAA0-AF544B64E811Q42089651-7811FF21-BDCE-4438-B862-C2B042642D6BQ42455010-D10F3F01-50AA-487A-9AC8-FEDC4D66B5D7Q42460596-E65B70D8-5F7C-4DF9-9E6E-5C8D1C98AE04Q42466818-3D5DF318-266D-4AE2-A281-F04B72B9F3F7Q43437015-2246C21E-F532-4C88-AD1A-46E46AA7E699Q45752807-1C5ABA37-AB0C-4EE5-8749-B22813876157Q47859685-466ECE5C-AE2A-4451-8480-E1DFCAF5C9AEQ48377098-2E682D76-B0E0-4A39-856E-AB413B4BF85CQ50514499-6D831C0E-1658-4E7D-BF40-1DC4F6E5D6B3Q54698981-6AA50DBA-887F-4F70-95E6-674BD47D3217Q55130069-4651CB9E-ABB0-47EA-9DB2-E4039740E285
P2860
The melanocortin 1 receptor and the UV response of human melanocytes--a shift in paradigm.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 February 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@en
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@nl
type
label
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@en
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@nl
prefLabel
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@en
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@nl
P2093
P2860
P1476
The melanocortin 1 receptor an ...... anocytes--a shift in paradigm.
@en
P2093
Ana Luisa Kadekaro
James Knittel
Renny Starner
Viki B Swope
Zalfa A Abdel-Malek
P2860
P304
P356
10.1111/J.1751-1097.2008.00294.X
P577
2008-02-11T00:00:00Z