Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis
about
Developmental roles of tribbles protein family membersFollistatin-like protein 1 regulates chondrocyte proliferation and chondrogenic differentiation of mesenchymal stem cellsMammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistanceShikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathwayBiological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells.Protein kinase B and extracellular signal-regulated kinase contribute to the chondroprotective effect of morroniside on osteoarthritis chondrocytesAging and osteoarthritis: an inevitable encounter?Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways.Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signallingBiology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes.Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation.C/EBP homologous protein drives pro-catabolic responses in chondrocytes.TRB3 mediates renal tubular cell apoptosis associated with proteinuria.Hyperbaric oxygen protects mandibular condylar chondrocytes from interleukin-1β-induced apoptosis via the PI3K/AKT signaling pathway.Prostaglandin E2 and prostaglandin F2α differentially modulate matrix metabolism of human nucleus pulposus cells.A homeostatic function of CXCR2 signalling in articular cartilage.Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis.A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neuronsCa2+-Dependent Endoplasmic Reticulum Stress Regulates Mechanical Stress-Mediated Cartilage Thinning.MicroRNA-218-5p as a Potential Target for the Treatment of Human Osteoarthritis.Tribbles Pseudokinase 3 Induces Both Apoptosis and Autophagy in Amyloid-β-induced Neuronal Death.The inhibition of PLCγ1 protects chondrocytes against osteoarthritis, implicating its binding to Akt.Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis.Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.Zhuangguguanjie formulation protects articular cartilage from degeneration in joint instability-induced murine knee osteoarthritis.
P2860
Q26828448-7F654ED2-9818-4073-948F-9F10062451B6Q28236139-B5A62548-79AF-48D1-91C6-8A0AF6D38D8FQ33727391-E94AAB4A-E9CC-4ADA-9618-9BC3A8329835Q35145099-D8AB9421-901B-4A3B-88CD-5BB4AB49DE0DQ35899103-6A941CB5-3D85-417B-83A5-B9059768A88DQ35995086-F24FF184-0A14-4971-893B-1DE75184458FQ36036777-470EC4F4-87AF-4EF0-975D-6F00A9B050BBQ36682215-BD02BCEF-C4D3-4ACE-9D78-A55501C791FBQ37481737-EF468C26-3719-4C90-93A8-DAAFB67EA26AQ37595305-30DEB61F-E46F-4D74-AE0C-76B51EC6E45DQ37761694-A2765594-F495-4944-9945-7F4CF3324EFFQ37845436-099A97CF-1BE2-4976-B88F-8138C85650DDQ38643818-66BD25B0-B65C-4098-985B-5AA263853C41Q38985277-D4C72012-FCFA-4037-8C9A-495D0AF838DEQ39140776-0ACD08D7-7173-4F31-A80A-55DF8B9EF279Q39595699-A1A3D28C-CBE9-49E6-B98E-A0C01A0AA8F6Q41989544-87C02A04-84DF-499A-83EC-B72B87611129Q42135414-1659547C-8797-4586-A4AB-489B29ED851EQ42844976-E7524FF4-CF8B-4E96-9C5A-5B45FBE625D9Q45049380-8F45F162-EE4E-4D6A-9C96-D95DE7DA3D40Q47766972-24A0B2A6-2CDF-4B65-9C6F-E3C4F7EA5C14Q49259151-DE51F4F3-C69E-409E-B068-C1CC11877903Q50053057-46F1AE5A-8632-4074-A04E-9FDFFAC61C75Q52668822-16954523-2945-4D70-BF46-E9EB8E48C0FEQ54176920-B922FDE6-EBEB-4A45-89B7-9CB7A630D3B8Q54964471-D1700D2E-E06D-4376-BBE9-01F365F9008D
P2860
Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Increased expression of the Ak ...... val and proteoglycan synthesis
@en
Increased expression of the Ak ...... al and proteoglycan synthesis.
@nl
type
label
Increased expression of the Ak ...... val and proteoglycan synthesis
@en
Increased expression of the Ak ...... al and proteoglycan synthesis.
@nl
prefLabel
Increased expression of the Ak ...... val and proteoglycan synthesis
@en
Increased expression of the Ak ...... al and proteoglycan synthesis.
@nl
P2093
P2860
P356
P1476
Increased expression of the Ak ...... val and proteoglycan synthesis
@en
P2093
Cathy S Carlson
David Long
Hee-Jeong Im
John D Cravero
Raghunatha R Yammani
Richard F Loeser
P2860
P304
P356
10.1002/ART.24225
P577
2009-02-01T00:00:00Z