Augmentation of morphine-induced sensitization but reduction in morphine tolerance and reward in delta-opioid receptor knockout mice.
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15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuseOpioid receptors: toward separation of analgesic from undesirable effectsBrain Reward Circuits in Morphine AddictionHow to design an opioid drug that causes reduced tolerance and dependence.Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat.Hormonal regulation of delta opioid receptor immunoreactivity in interneurons and pyramidal cells in the rat hippocampus.Recent advances on the δ opioid receptor: from trafficking to function.Implication of delta opioid receptor subtype 2 but not delta opioid receptor subtype 1 in the development of morphine analgesic tolerance in a rat model of chronic inflammatory pain.The delta opioid receptor: an evolving target for the treatment of brain disorders.Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide.Reward processing by the opioid system in the brain.The γ-aminobutyric acid type B (GABAB) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens.Upregulation of nerve growth factor in central amygdala increases sensitivity to opioid rewardOpioid receptors: distinct roles in mood disorders.Impaired hippocampus-dependent and facilitated striatum-dependent behaviors in mice lacking the δ opioid receptor.Pharmacological traits of delta opioid receptors: pitfalls or opportunities?Delta opioid receptors in brain function and diseasesSynthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities.Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior.Delta-opioid receptor antagonists prevent sensitization to the conditioned rewarding effects of morphine.Opiate-agonist induced taste aversion learning in the Fischer 344 and Lewis inbred rat strains: evidence for differential mu opioid receptor activation.Preclinical evidence of new opioid modulators for the treatment of addiction.Functional relevance of μ-δ opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology.The role of δ-opioid receptors in learning and memory underlying the development of addiction.Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src.Delta Opioid Receptors: Learning and Motivation.Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers.Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist propertiesCues predicting drug or food reward restore morphine-induced place conditioning in mice lacking delta opioid receptors[The endogenous opioid system and drug addiction].Chronic Morphine Reduces Surface Expression of δ-Opioid Receptors in Subregions of Rostral Striatum.Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization.Effect of Sinomenine on the Morphine-Dependence and Related Neural Mechanisms in Mice.Clinical opioids differentially induce co-internalization of μ- and δ-opioid receptors.Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.
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Augmentation of morphine-induced sensitization but reduction in morphine tolerance and reward in delta-opioid receptor knockout mice.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@en
Augmentation of morphine-induc ...... opioid receptor knockout mice.
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type
label
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@en
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@nl
prefLabel
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@en
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@nl
P2860
P356
P1476
Augmentation of morphine-induc ...... opioid receptor knockout mice.
@en
P2093
T S Shippenberg
V I Chefer
P2860
P2888
P304
P356
10.1038/NPP.2008.128
P407
P577
2008-08-13T00:00:00Z