Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer. - Wikidata - awgldk - TriplyDB

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

http://www.wikidata.org/entity/Q37093018

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Novel Molecular Markers for Breast Cancer Aberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast Cancer Haploinsufficient tumor suppressor genes.From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform.Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.DMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1.Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancer Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy Aberrant expression of cyclin D1 in cancer.Anticancer Effects of the Marine Sponge Lipastrotethya sp. Extract on Wild-Type and p53 Knockout HCT116 Cells Clinical applications of mouse models for breast cancer engaging HER2/neu.Transcription factors that interact with p53 and Mdm2 Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α.Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu.PRL-3 promotes breast cancer progression by downregulating p14ARF-mediated p53 expression.

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Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

http://www.wikidata.org/entity/Q37093018

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articolo scientifico

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scientific article published on 08 October 2012

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@en

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@nl

type

label

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@en

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@nl

prefLabel

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@en

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

@nl

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Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer

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S Zhu

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P2860

Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)

Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism

The Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.

Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance.

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4120-4129

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10.1038/ONC.2012.423

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