Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans
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Glycotherapy: new advances inspire a reemergence of glycans in medicineImmune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesThe use of glycoinformatics in glycochemistryEfficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycanExpeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylationLC-MS/MS biopharmaceutical glycoanalysis: identification of desirable reference material characteristics.The Amazing Transglycosylation Activity of Endo-β-N-acetylglucosaminidasesAnalysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism.Convergent synthesis of homogeneous Glc1Man9GlcNAc2-protein and derivatives as ligands of molecular chaperones in protein quality control.Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.Emerging technologies for making glycan-defined glycoproteinsTransglycosylation Activity of Glycosynthase Mutants of Endo-β-N-Acetylglucosaminidase from Coprinopsis cinerea.Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptidesA two-step enzymatic glycosylation of polypeptides with complex N-glycansEndo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins.Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein.Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.Enzymatic transglycosylation for glycoconjugate synthesis.Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.Toward automated oligosaccharide synthesis.Recent advances in glycotechnology for glycoconjugate synthesis using microbial endoglycosidases.Chemoenzymatic Synthesis and Receptor Binding of Mannose-6-Phosphate (M6P)-Containing Glycoprotein Ligands Reveal Unusual Structural Requirements for M6P Receptor Recognition.Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells.Recent progress in the field of neoglycoconjugate chemistry.Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.Towards the next generation of biomedicines by site-selective conjugation.Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies.Chemoenzymatic Fc glycosylation via engineered aldehyde tags.The ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling.Synthetic glycopeptides and glycoproteins with applications in biological research.Generation of a Mutant Mucor hiemalis Endoglycosidase That Acts on Core-fucosylated N-Glycans.Glycosylation of pramlintide: synthetic glycopeptides that display in vitro and in vivo activities as amylin receptor agonists.
P2860
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P2860
Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Glycosynthases enable a highly ...... rying intact natural N-glycans
@en
Glycosynthases enable a highly ...... ying intact natural N-glycans.
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type
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Glycosynthases enable a highly ...... rying intact natural N-glycans
@en
Glycosynthases enable a highly ...... ying intact natural N-glycans.
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prefLabel
Glycosynthases enable a highly ...... rying intact natural N-glycans
@en
Glycosynthases enable a highly ...... ying intact natural N-glycans.
@nl
P2093
P2860
P356
P1476
Glycosynthases enable a highly ...... rying intact natural N-glycans
@en
P2093
Kenji Yamamoto
Lai-Xi Wang
Midori Umekawa
Xinyu Zhang
P2860
P304
P356
10.1021/JA8074677
P407
P50
P577
2009-02-01T00:00:00Z