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Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistryRelationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreasMethods to Increase the Metabolic Stability of (18)F-RadiotracersManganese-enhanced magnetic resonance imaging detects declining pancreatic β-cell mass in a cyclophosphamide-accelerated mouse model of type 1 diabetes.Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging.Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis.Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo.Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonographyEnhanced cholinergic response in pancreata of nonhuman primates with impaired glucose tolerance shown on [18F]fluorobenzyltrozamicol positron emission tomographyDual radiotracer analysis of cholinergic neuronal changes in prediabetic mouse pancreasPET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133)New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2)Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligandsDecreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PETSynthesis and evaluation of [18F]exendin (9-39) as a potential biomarker to measure pancreatic β-cell mass.Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain.Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis.A Novel Potential Positron Emission Tomography Imaging Agent for Vesicular Monoamine Transporter Type 2Radioiodinated naphthylalanine derivatives targeting pancreatic beta cells in normal and nonobese diabetic mice.Cross-sectional and Test-Retest Characterization of PET with [(18)F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes.Imaging of beta-cell mass and functionThe utility of [(11)C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal-jejunal bypassIn vivo beta-cell imaging with VMAT 2 ligands--current state-of-the-art and future perspective.11C-dihydrotetrabenazine PET of the pancreas in subjects with long-standing type 1 diabetes and in healthy controls.Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET.Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled ExendinBioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation.Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-glipizide.Advances in beta-cell imagingSpecies-specific vesicular monoamine transporter 2 (VMAT2) expression in mammalian pancreatic beta cells: implications for optimising radioligand-based human beta cell mass (BCM) imaging in animal models.Imaging the islet graft by positron emission tomography.Beta-cell imaging: call for evidence-based and scientific approach.Imaging beta-cell mass and function in situ and in vivo.Genetically engineered pig models for diabetes research.Pancreatic β-cell imaging in humans: fiction or option?Failed PET Application Attempts in the Past, Can We Avoid Them in the Future?On the use of [18F]DOPA as an imaging biomarker for transplanted islet mass.Striated muscle as implantation site for transplanted pancreatic islets.Distribution of pancreatic B cell imaging agent (99m)Tc-DTPA-NGN2 in the body and animal experimental research on pancreatic B cell functional imaging.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2006
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@en
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@nl
type
label
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@en
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@nl
prefLabel
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@en
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@nl
P2093
P2860
P1476
Visualizing pancreatic beta-cell mass with [11C]DTBZ.
@en
P2093
Agata Jurewicz
Alan Herron
Anthony Raffo
Antonella Maffei
Fabiola Souza
Kevan Herold
Mark Adam Hardy
Michael Kilbourn
Norman Ray Simpson
P2860
P304
P356
10.1016/J.NUCMEDBIO.2006.07.002
P577
2006-10-01T00:00:00Z