Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.
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Hallmarks of cancer and AU-rich elementsCombinatorial Control of mRNA Fates by RNA-Binding Proteins and Non-Coding RNAsFlavivirus Infection Uncouples Translation Suppression from Cellular Stress ResponsesVersatility of RNA-Binding Proteins in CancerSystematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cellsEffect of chronic contractile activity on mRNA stability in skeletal musclePhosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samplesRibavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.HuR function in disease.Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells.Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1The oncogene eIF4E: using biochemical insights to target cancer.Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium ProgramThe leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) does not activate transcription in mammalian mitochondria.Anti-oncogenic potential of the eIF4E-binding proteins.Translational control of immune responses: from transcripts to translatomes.Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysisTargeting translation: eIF4E as an emerging anticancer drug target.Expression of the ELAV-like protein HuR in the cytoplasm is associated with endometrial carcinoma progression.Targeting of protein translation as a new treatment paradigm for prostate cancer.Overexpression of the human antigen R suppresses the immediate paradoxical proliferation of melanoma cell subpopulations in response to suboptimal BRAF inhibition.Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development.Expression of eukaryotic initiation factor 4E and 4E binding protein 1 in colorectal carcinogenesis.mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells.Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer.Major splice variants and multiple polyadenylation site utilization in mRNAs encoding human translation initiation factors eIF4E1 and eIF4E3 regulate the translational regulators?Analysis of eIF4E and 4EBP1 mRNAs in head and neck cancer.
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Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 December 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@en
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@nl
type
label
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@en
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@nl
prefLabel
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@en
Stability of eukaryotic transl ...... ity is dysregulated in cancer.
@nl
P2093
P2860
P356
P1476
Stability of eukaryotic transl ...... vity is dysregulated in cancer
@en
P2093
Katherine L B Borden
Lucy A Skrabanek
Mathieu Tremblay
Nadeem Siddiqui
Slobodanka Orolicki
Trang Hoang
P2860
P304
P356
10.1128/MCB.01532-08
P407
P577
2008-12-29T00:00:00Z